Protein Alignment Mi-2 and rad54l

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001001241.1
• Gene: rad54l / 407922
• XenbaseID: XB-GENE-979988
• Length: 742
• Species: Xenopus tropicalis
• Alignment Length: 722
• Identity: 197/722 - (27%)
• Similarity: 326/722 - (45%)
• Gaps: 123/722 - (17%)

  Fly   568 EESLDEADTRYKRIQRHKDKVGMKANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDGS---- 628
            ||..::|..:.||:..:||                ..:|.:.|....:.:|.|..|..|..
 Frog    22 EEWCEDAVPKRKRLSSNKD----------------IRENWISPFRKPLAQVTNRPTCLDSKQHEA 70

  Fly   629 --TMYLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQ---DLRAVCTSETTQSRSKKSKKGRKSK 688
              ...|.|..::|                   |..||   .|||:..          .|.|.:..
 Frog    71 FIRSILSKPFKIP-------------------IPNYQGGLGLRALGI----------KKAGIRRA 106

  Fly   689 LKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFL---EGTGMQLHPYQIEGINWL-------R 743
            |. :..|:..:..|.||.......||...|..|..:   ...|..|.|:|.||:.:|       |
 Frog   107 LH-DPFEEGALVLYEPPQLSAHDLLKVDKEKVPVHVVVDPVLGKVLRPHQREGVKFLWECVTGRR 170

  Fly   744 YSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGP----FLVAVPLSTLVNWEREFELWAP 804
            .|...|  :|:|||||||||:|.:|.:::|.::.....|    .:|..|.|.:.||..|...|
 Frog   171 ISGSHG--SIMADEMGLGKTLQCITLIWTLLRQSPDAKPEIEKAVVVCPSSLVKNWYNEVSKW-- 231

  Fly   805 DFYCITYIGDKDSRAVI---RENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACL- 865
                   :|.:.....|   .:.|:..:..........|:.:.     :|:.|||...:.|..|
 Frog   232 -------LGGRIQPLAIDGGSKEEIDKKLSGFMNQHGMRVPSA-----ILIISYETFRLHAEVLH 284

  Fly   866 -GSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFND 929
             ||:  .:::.||.||||:::::.::.|||.....::|::|||:||:|.|.|.|::|::......
 Frog   285 RGSV--GLVICDEGHRLKNSENQTYQALNSLNTVRRVLISGTPIQNDLLEYFSLVHFVNAGILGT 347

  Fly   930 LQAFQGEF---------ADVSK------EEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRV 979
            .|.|:..|         ||.|.      ||::|.|..::...::||....:.|.:|.|.|.:|..
 Frog   348 AQEFKKRFEIPILKGRDADASAADRQKGEEKLKELIGVVNRCLIRRTSDILSKYLPVKIEQVVCC 412

  Fly   980 ELSAMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYL-FPSAAEEATTAAGGL- 1042
            .|:.:|.:.||..|.:...|.:...|..|.|.::.:..|||.||||.| :....||.....|.|
 Frog   413 RLTPLQSELYKLFLKQAKPAEDLNEGKISVSSLSSITSLKKLCNHPSLIYEKCVEEEEGFQGALN 477

  Fly  1043 -----YEINSL-TKAAGKLVLLSKMLKQLKA-QNHRVLIFSQMTKMLDILEDFLEGEQYKYERID 1100
                 |...|: .:.:||:::|..:|...:: .:.:|::.|..|:.||:.|......:|.|.|:|
 Frog   478 LFPSGYSTKSVEPQLSGKMLVLDYILAVTRSTSSDKVVLVSNYTQTLDLFEKLCRTRRYLYVRLD 542

  Fly  1101 GGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHR 1165
            |.::...|.:.::|||:|.:.:|:|:||::|||.|:||..|:.::::|.||||.||.||.:|..|
 Frog   543 GTMSIKKRAKIVERFNSPSSPEFIFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWR 607

  Fly  1166 IGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFG----- 1225
            .||.....|||.::..::||::.|....|..|:..||......: .:|:..||.::....
 Frog   608 DGQKKTCFIYRLLSTGTIEEKIFQRQTHKKALSSCVVDEEQDVE-RHFSIGELKELFILNENTTS 671

  Fly  1226 -TEDLFK 1231
             |.|.||
 Frog   672 DTHDKFK 678

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367
		PHD1_CHD_II	380..422	CDD:277006
		PHD2_CHD_II	440..482	CDD:277007
		CD1_tandem_CHD3-4_like	487..557	CDD:349314
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	11/62 (18%)
		PLN03142	720..>1234	CDD:215601	165/561 (29%)
		DUF1087	<1292..1334	CDD:461922
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
rad54l	NP_001001241.1	Rad54_N	<74..>121	CDD:430137	14/76 (18%)
		HepA	<147..645	CDD:440319	156/515 (30%)
		DEXHc_RAD54A	151..393	CDD:350825	72/259 (28%)