|
Fly 143 EEELQSLTTYKAFMHHVRPILQKENPKIAAPKLVMLVAAKWREFCESNPHIQQEGGAAGSGGSAG 207
:...|.|.|......| |.|.:.:| .:||.|.......|..:..
Mouse 499 QPSFQQLPTCPPLQPH--PGLHQSSP--------------------PHPHHQPWAQLHPSPQNTP 541
Fly 208 QARSVTGDEPEEP-----------RSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGK 261
|...|....|.|| .|:::::..|.|| |..::|::.::::::||.....:|...
Mouse 542 QKVPVHQHSPSEPFLEKPVPDMTQVSAQNAQLVKSDD-YLPSIEQQPQQKKKKKKNNHIAAGDSS 605
Fly 262 KG----RRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEFERMLQKSDDSADEKEAPV 322
|| ..|.| ::.:.|.:...|.|.||:......:...| .|......||:.|.
Mouse 606 KGFGKDDFPGG----VENQELRRNSLDVSQEEKKKKKRPKVKKD-------PKESKEPKEKKEPK 659
Fly 323 SSKADNSAPAAQDDGSGAPVVRKKAKT---KIGNKFKKKNK--------LKKTKNFPEGEDGEHE 376
:.||.......:: ||||| |..:..|..|| |||..|..:.|..|:.
Mouse 660 TPKAPKIPKEPKE---------KKAKTVTPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENS 715
Fly 377 HQDYCEVCQQGGEIILCDTCPRAYHLVCLEPELDEPP------------------EGKWSCPHCE 423
..| .|.|.: ..||.||.| :.::.....|
Mouse 716 DLD--------------KTPPPS-----PAPEEDEDPGVQKRRSSRQVKRKRYTEDLEFKISDEE 761
Fly 424 ADGGAAEEED------DDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLDTIPDGDWRCPRC 482
||...|...| ..|.|| .|..:|
Mouse 762 ADDADAAGRDSPSNTSQSEQQE--SVDAEG----------------------------------- 789
Fly 483 SCPPLTGKAEKIITWRWAQRSNDDGPSTSKGSKNSNSRVREYFIKWHNMSYWHCEWVPEVQLDVH 547
|: .|||::.|..::..:.|... .|.|:::|:.|.||.||:|. .|:
Mouse 790 ---PV---VEKIMSSRLVKKQKESGEEV---------EVEEFYVKYKNFSYLHCQWA-SVE---- 834
Fly 548 HPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRIQRHKDKVGMKANDDAEVLEERFYKNGVKPEW 612
|:|:..:.:: :|:|.|.|.| ::...:|:.::.| .|::
Mouse 835 ------------DLEKDKRIQQ----------KIKRFKSKQG-QSKFLSEIEDDLF-----NPDY 871
Fly 613 LIVQRVINHRTARD--GSTM--YLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSET 673
:.|.|:::...:.| |..: |||||..|||:.|||| |:|.||
Mouse 872 VEVDRIMDFARSTDDRGEPVIHYLVKWCSLPYEDSTWE--------LKQDID------------- 915
Fly 674 TQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEG 738
::|.....||...:.|...| |:|..|..||.|....:.... :|..||:||
Mouse 916 ------QTKIEEFEKLMSREPETERV-------ERPPADDWKKSESSREYKNNN--KLREYQLEG 965
Fly 739 INWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWA 803
:|||.::|....:.|||||||||||||::||||.:|.:| ..|||||..||||:.||||||..|.
Mouse 966 VNWLLFNWYNMRNCILADEMGLGKTIQSITFLYEIYLKG-IHGPFLVIAPLSTIPNWEREFRTWT 1029
Fly 804 PDFYCITYIGDKDSRAVIRENELSFEE---GAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACL 865
:...:.|.|.:.||..|:..|:.|:: ..|:|| |||:.::|::|:|..|...|
Mouse 1030 -ELNVVVYHGSQASRRTIQLYEMYFKDPQGRVIKGS---------YKFHAIITTFEMILTDCPEL 1084
Fly 866 GSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDL 930
.:|.|..:|:|||||||:...|....|....:.:|:|||||||||.:||||.||:||...:|...
Mouse 1085 RNIPWRCVVIDEAHRLKNRNCKLLEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSE 1149
Fly 931 QAFQGEFADVSKEEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTK 995
..|..||.|:..||||::|..:|.|.||||||.||.||:..|.|.|:.|||:.:|||:|:.||.|
Mouse 1150 TTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEK 1214
Fly 996 NYEALNSKSGGGSC---SLINIMMDLKKCCNHPYLFPSAAE-------EATTAAGGLYEINSLTK 1050
|:..|: .|||.. :|:|.||:|:||||||||...|.| |...|....:::.::.:
Mouse 1215 NFTFLS--KGGGQANVPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQ 1277
Fly 1051 AAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRF 1115
|||||||:.|:|.:|||..|||||||||.:.||||||:|...:|.||||||.:.|.|||.|||||
Mouse 1278 AAGKLVLIDKLLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRF 1342
Fly 1116 NAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTR 1180
:.|.:.:|||||.||||||||||..|||.||:||||||.||:||.:|.|||||:..|.|||.:||
Mouse 1343 SKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITR 1407
Fly 1181 NSVEERVTQVAKRKMMLTHLVVRPGMGGKGA-----NFTKQELDDILRFGTEDLFKEDDKEEAIH 1240
||.|..:...|..|:.|...|::...|.:.| ..:|:|::|:||.|......:::.|.:..
Mouse 1408 NSYEREMFDKASLKLGLDKAVLQSMSGRENATNGVQQLSKKEIEDLLRKGAYGALMDEEDEGSKF 1472
Fly 1241 YDDKAVAELLDRTNRGIEEKESWANEYLSSFKVASYATKEEEEEEETEIIKQDAENSDPAYWVKL 1305
.::.....||.||:....|.|... |:|..||:..... :.|....||.:|.|.
Mouse 1473 CEEDIDQILLRRTHTITIESEGKG----STFAKASFVASGN---------RTDISLDDPNFWQKW 1524
Fly 1306 LRHHYEQHQEDVGRSLGKGK------RVRKQVNYTDGGVVAADTTRDDSNWQDNGSEYNSEYSAG 1364
.: :.:.|:....|:.. |||||... |||.
Mouse 1525 AK----KAELDIDALNGRNNLVIDTPRVRKQTRL---------------------------YSAV 1558
Fly 1365 SDEDGGDDDFDD-QNGAERKAKRRLERRDDRPLPPLLA---RVGGNIEVLGF--------NARQR 1417
.::: ..:|.| ::.:|.|...:..|..|:......: ||..|:.|.|: :.|.:
Mouse 1559 KEDE--LMEFSDLESDSEEKPCAKPRRPQDKSQGYARSECFRVEKNLLVYGWGRWTDILSHGRYK 1621
Fly 1418 K--------SFLNAIMRYGM------------------PPQDA-----FNSQWLVRDL-RGKSER 1450
: :...||:.|.: |..|. .|...|...: ||:..:
Mouse 1622 RQLTEQDVETICRAILVYCLNHYRGDENIKSFIWDLITPTADGQTRALLNHSGLSAPVPRGRKGK 1686
Fly 1451 NFKAYVSLFMRHLCEPGADNAETFA----DGVPREGLSRQH-------VLTRIGVMSLIRKKV-- 1502
..||..: :|...:|...| |.:.:|...::| ||.|:.::..:|::|
Mouse 1687 KVKAQST-------QPVVHDAHWLASCNPDALFQEDSYKKHLKHHCNKVLLRVRMLYYLRQEVIG 1744
Fly 1503 -QEFEHINGYYSMPELILKPCEPVRSALKQDVAALEAPPTGGNVDKSAT-----------TSNSV 1555
|..:.:.|..|....:..| ||..:.:..|....|| |||.. .|...
Mouse 1745 DQAEKILEGADSSEADVWIP-EPFHAEVPTDWWDREA-------DKSLLIGVFKHGYEKYNSMRA 1801
Fly 1556 TPA------TSAAPSPAPASEK---------GEDKDKDSEKEKDKTSAEKSEVKQEQEAEEDKKP 1605
.|| .....:.|.|:|: |:..:.|.|.|..:....::..|.|.: |....|
Mouse 1802 DPALCFLERVGMPDAKAIAAEQRGTDMLADGGDGGEFDREDEDPEYKPTRAPFKDEID-EFANSP 1865
Fly 1606 GDVKQENPVEEAAGDTKPSDAE-------------------------------------VKTEVA 1633
.:.|:|:....::|....|:|| :||:..
Mouse 1866 AEDKEESMEVHSSGKHSESNAELGQLYWPNTSTLTTRLRRLITAYQRSYKRQQMRQEALMKTDRR 1930
Fly 1634 KTEPKEETKDPEVKEEPKTEEK-----EKEKVDDKKPIPPTTVIDDDDDDVMIVKED-------- 1685
:..|:||.:..|.:.|....|| .:|:.|..:.:....||.|. ||:.
Mouse 1931 RRRPREEVRALEAEREAIISEKRQKWTRREEADFYRVVSTFGVIFDP------VKQQFDWNQFRA 1989
Fly 1686 -GELEKPSASS---------------------PKDQKA-VAAATSAATGATGKGAEDSLEVLKRK 1727
..|:|.|..| |:|:.. :|:.....|..........:|:| ||
Mouse 1990 FARLDKKSDESLGKYFSCFVAMCRRVCRMPAKPEDEPPDLASLIEPITEERASRTLYRIELL-RK 2053
Fly 1728 FMFNIADGGFTELHTLWLNEE-KAAVPGREYEIWHR--RHDYWLLAGIVTHGYGRWQDIQNDIRF 1789
....: ||...|::. |...|..:...|.. |||..||.|...||..|.. :
Mouse 2054 IREQV-------LHHPQLSDRLKLCQPSLDLPEWWECGRHDRDLLVGAAKHGVSRTD-------Y 2104
Fly 1790 AIINEPFKMDVGKGNFLEIKNKF--------------LARRF----KLLEQALVIEEQLRRAAYL 1836
.|:|:| :.:||:....| ||..| .::..|.|.||:....|.
Mouse 2105 HILNDP------ELSFLDAHKSFAQNRGASTVPPLNTLAMGFGQTPPVISSAHVHEEKAMEQAE- 2162
Fly 1837 NLAQDPSH-PAMSLN-----------ARFAEVECLAESHQHLSKESLAG-----NKPANAVLHKV 1884
..|::..| ||...: |:..:.||..|:.. .|..|.| :..:.:|..|.
Mouse 2163 GKAEECEHSPAKERSDGKEEEEEAGGAKDGKQECEVEASS--VKGELKGVEGSADPGSKSVSEKG 2225
Fly 1885 LNQLEE--LLSDMKSDVSRLPATLARIPPVAQRLQMSERSILSRLAATAGNASNAA 1938
..:.|| |..|.||:.|..| |...:|| ..|....|||:
Mouse 2226 SEEDEEEKLEDDDKSEESSQP----------------EAGAVSR-GKTFDEESNAS 2264
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