Protein Alignment Mi-2 and rad54b

DIOPT Version :10

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: NP_001121509.1
• Gene: rad54b / 100158622
• XenbaseID: XB-GENE-5839240
• Length: 897
• Species: Xenopus tropicalis
• Alignment Length: 993
• Identity: 245/993 - (24%)
• Similarity: 399/993 - (40%)
• Gaps: 225/993 - (22%)

  Fly   406 EPELDEPPEGKWSCPHCEADGGAAEEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLD 470
            :|....|.:...:||..|......:..|..:...                  .|:...|   .|:
 Frog    17 KPRFIPPGKVNAACPDTETKHSITDSTDKKQLSS------------------RAFEERC---GLN 60

  Fly   471 TIPDGDWRCPRC--SCPPLTGKAEKIITWRWAQRSNDDGPSTSKGSKNSNSRVREYF-IKWHNMS 532
            |:      .||.  |..||:.....|:|.....||........|.....:|...:|| :.|...|
 Frog    61 TV------LPRAEGSAQPLSSNKTAIMTSVPVCRSVAGAIKEHKNEVEESSSFAKYFSVVWCKAS 119

  Fly   533 -YWHCEWVPE-VQLDVHHPLMIRSFQRKYDMEEPPKFE----ESLDEADTRYKRIQRHKDKVGMK 591
             ..|.:|..: |.:.....:.::..:.| |:.:...::    |||:|.         |...:|.|
 Frog   120 KKKHKKWEGDAVLIAKGRAVTLKDMEGK-DIGKGTGYKIKDLESLEEG---------HTLMIGGK 174

  Fly   592 ANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDGSTMYLVKWRELPYDKSTWEEEGDDIQGLR 656
            ..:...::....|.:|         |..:.......||
 Frog   175 EIEVMSIMSPEDYNSG---------RCFHSVVTSPAST--------------------------- 203

  Fly   657 QAIDYYQDLRAVCTSETTQSRS-----KKSKKGRKSKLKVEDDEDRPVKHYTPPPE-----KPTT 711
                         .||:.|.:.     :..:||...:...::.::...:|....|.     |||.
 Frog   204 -------------PSESIQMKPFTNPLRNDRKGASKENMFKELQNIKPRHDPCAPNAFVMPKPTQ 255

  Fly   712 DLKKKYEDQPAFLEGTGM-------------QLHPYQIEGINWLRYSWGQGI------DTILADE 757
            ..:..|..       ||:             .|.|:|.|||.:| |....|:      ..|||||
 Frog   256 HHQWAYNK-------TGLPIVDVVVDPYLAVHLRPHQKEGILFL-YECVMGMRVNERFGAILADE 312

  Fly   758 MGLGKTIQTVTFLYSLYKEGHCRG-----PFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDS 817
            ||||||:|.::.:::|.::|...|     ..|:..|.|.:.||.:||:.|         :|.:..
 Frog   313 MGLGKTLQCISLIWTLIRQGPYGGKPVIKKALIVTPGSLVKNWRKEFQKW---------LGTERI 368

  Fly   818 RAVIRENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAHRLK 882
            |....:.:...||         .:::..|  :||:.|||::......:.|:|:.|::.||.||||
 Frog   369 RVFAVDQDHKVEE---------FMKSPLY--SVLIISYEMLLRCLEQIQSLDFDVVICDEGHRLK 422

  Fly   883 SNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAFQGEFADV---SK-- 942
            :...|....|.|.|.:.:::|:|||:||:|:|.|.|:.|::......|..::..|.:.   |:
 Frog   423 NTSIKTTSALASLTCSKRIILSGTPVQNDLQEFFALIEFVNPAALGSLSTYRKIFEEPIIRSREP 487

  Fly   943 ----------EEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNY 997
                      ||:...|..:.|..:|||.:..:.|.:|.|.|.||....|..|...|:
 Frog   488 TATTEEKNLGEERAAELARLTGLFILRRTQEVINKFLPPKIESIVFCRPSQFQLDLYR------- 545

  Fly   998 EALNSK--------SGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAG----GLYEINSLTK 1050
            :.|||:        ||..|..|:.|.. |||.||||:|.....:..:|...    .|||  |:.:
 Frog   546 KLLNSRTVKSCLLGSGESSPHLVCIGA-LKKLCNHPFLLFRTIQGKSTNPDQDEHNLYE--SVAE 607

  Fly  1051 A--------------AGKLVLLSKMLKQLK--AQNHRVLIFSQMTKMLDILEDFLEGEQYKYERI 1099
            .              :|||::||.:|.:::  :.:.||::.|..|:.|:||:|......|...|:
 Frog   608 VFPQDYDGAKISESESGKLLVLSNLLSRIRELSPSERVVLVSNYTQTLNILQDLCNQHGYSCTRL 672

  Fly  1100 DGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAH 1164
            ||....|.||..:|.||:..:..|:||||::|||:|:||..|..:|:||.||||.|||||.:|..
 Frog   673 DGQTPVTQRQHIVDGFNSKYSTDFIFLLSSKAGGVGLNLIGASHLILYDLDWNPANDIQAMARVW 737

  Fly  1165 RIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFG---- 1225
            |.||.:.|.|||.:|..|:||::.|....|..|:..||......:...|:..||.::....
 Frog   738 RDGQRHTVHIYRLLTTGSLEEKIYQRQISKQGLSGAVVDLTKKSEHIRFSLDELRNLFTLHEDTD 802

  Fly  1226 --TEDLFKEDDKEEAIHYDDKAVAELLDRT-NRGIEEKESWANEYLSSFKVASYATKEEEEE--- 1284
              |.||.:.|......|.|......|:.|: ..|:.:.:...|..:|......:.:.::..|
 Frog   803 CVTHDLLQCDCTITNCHSDGSPQKPLIHRSCQLGLHQDQLNKNFSMSELMQWKHFSGQQNTEDPF 867

  Fly  1285 -----EETEIIKQDAENS 1297
                 |....:.|:..||
 Frog   868 LQMGKEHISFVFQNTTNS 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..191	CDD:462357
		TNG2	<282..422	CDD:227367	4/15 (27%)
		PHD1_CHD_II	380..422	CDD:277006	4/15 (27%)
		PHD2_CHD_II	440..482	CDD:277007	5/41 (12%)
		CD1_tandem_CHD3-4_like	487..557	CDD:349314	14/72 (19%)
		CD2_tandem_CHD3-4_like	610..664	CDD:349309	3/53 (6%)
		PLN03142	720..>1234	CDD:215601	179/586 (31%)
		DUF1087	<1292..1334	CDD:461922	3/6 (50%)
		CHDII_SANT-like	1380..1517	CDD:461920
		CHDCT2	1757..1902	CDD:462358
rad54b	NP_001121509.1	HepA	<277..776	CDD:440319	170/529 (32%)
		DEXHc_RAD54B	281..515	CDD:350824	74/254 (29%)