Protein Alignment Mi-2 and smarca1

DIOPT Version :9

• Sequence 1: NP_001014591.1
• Gene: Mi-2 / 40170
• FlyBaseID: FBgn0262519
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_002931866.2
• Gene: smarca1 / 100101797
• XenbaseID: XB-GENE-492011
• Length: 1034
• Species: Xenopus tropicalis
• Alignment Length: 1092
• Identity: 318/1092 - (29%)
• Similarity: 491/1092 - (44%)
• Gaps: 238/1092 - (21%)

  Fly   680 KSKKGRKSKL---------KVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQ 735
            |.||..|..|         :.|.:||..:.    ...:.|:::..::|:.|::::|.  .|..||
 Frog   106 KIKKDEKQNLLSAGDYRHRRTEQEEDEELL----SESRKTSNVCVRFEESPSYIKGG--TLRDYQ 164

  Fly   736 IEGINWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFE 800
            :.|:||:...:..||:.|||||||||||:||:..|..|....:..||.:|.||.|||.||..||:
 Frog   165 VRGLNWMISLYENGINGILADEMGLGKTLQTIALLGYLKHYRNIPGPHMVLVPKSTLHNWMNEFK 229

  Fly   801 LWAPDFYCITYIGDKDSRAV-IRENELSFEEGAIRGSKVSRLRTTQYKFNVLLTSYELISMDAAC 864
            .|.|....:..||||::||. ||:..:..|                  ::|.:||||::..:.:.
 Frog   230 RWIPSLCAVCLIGDKNARAAFIRDVMMPGE------------------WDVCVTSYEMVIKEKSV 276

  Fly   865 LGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFND 929
            ....:|..||:|||||:|:.:||...|:..:....:||||||||||||.||:.|||||..|.||.
 Frog   277 FKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWALLNFLLPDVFNS 341

  Fly   930 LQAFQGEFAD---VSKEEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKF 991
            .:.|...|..   :..::.|:|||.:|.|.:|||:|.:|.|::|.|.|..:.:.|..||:::|..
 Frog   342 AEDFDSWFDTNNCLGDQKLVERLHAVLKPFLLRRIKAEVEKSLPPKKEVKIYLGLGKMQREWYTK 406

  Fly   992 ILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINS-LTKAAGKL 1055
            ||.|:.:.|||........|:||:|.|:|||||||||..|      ..|..|..:: |...:||:
 Frog   407 ILMKDIDILNSAGKMDKMRLLNILMQLRKCCNHPYLFDGA------EPGPPYTTDTHLVYNSGKM 465

  Fly  1056 VLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRFNAPGA 1120
            |:|.|:|.:.|.|..|||||||||::||||||:.....|:|.|:||......|:.||:.||:|.:
 Frog   466 VVLDKLLPKFKEQGSRVLIFSQMTRVLDILEDYCMWRGYEYCRLDGQTPHEQREAAIETFNSPNS 530

  Fly  1121 QQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEE 1185
            .:|:|:||||||||||||||||.||:|||||||..|:||..|||||||...|.::|.:|.|:|||
 Frog   531 SKFIFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDRAHRIGQKKTVRVFRLITDNTVEE 595

  Fly  1186 RVTQVAKRKMMLTHLVVRPG--MGGKGANFTKQELDDILRFGTEDLFKEDDKEEAIHYDDKAVAE 1248
            |:.:.|:.|:.|..:|::.|  :..:.....|.|:..::|.|...:|...|.|    ..|:.:..
 Frog   596 RIVERAEIKLRLDSIVIQQGRLIDQQSNKLAKDEMLQMIRHGATHVFASKDSE----LTDEDITT 656

  Fly  1249 LLDRTNRG----IEEKESWANEYLSSFKVASYATKEEEEEEETEIIKQDAENSDPAYWVKLLRHH 1309
            :|:|..|.    .|..:......|.:|.|          :.||.:...:.|:            :
 Frog   657 ILERGERKTAEMAERLQKMGESSLRNFSV----------DTETSLYNFEGED------------Y 699

  Fly  1310 YEQHQEDVGRSLGKGKRVRKQVNY------------TDGGVVAADTTRDDSNWQD---------- 1352
            .|:.:..:...:...||.|| .||            ::..|..|.......|.||
 Frog   700 REKQKLSMMEWIEPPKRERK-ANYAVDAYFRDALRVSEPRVPKAPRPPKQPNIQDFQFFPPRLFE 763

  Fly  1353 ----------NGSEYNSEYSAGSDEDGGDDDFDDQNGAERKAKRRLERRDDRPLPPLLARVGGNI 1407
                      ....|....|:         |..:.:..:::.:|:::..:     ||.:......
 Frog   764 LLEKEILYYRKTIGYKVPRSS---------DLPNASQIQKEEQRKIDEAE-----PLCSEESEEK 814

  Fly  1408 EVL---GF---NARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEP 1466
            |.|   ||   |.|....|:.|..:||....|.     :.|::.||:......|..:|.....|
 Frog   815 EKLLTQGFTNWNKRDFNQFIKANEKYGRDDIDN-----IAREVEGKTPEEVMDYSGVFWERCNE- 873

  Fly  1467 GADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHINGYYSMPELILKPCEPVRSALKQ 1531
                                               :|:.|.|.......|..::....::.||..
 Frog   874 -----------------------------------LQDIEKIMAQIERGEARIQRRISIKKALDA 903

  Fly  1532 DVAALEAPPTGGNVDKSATTSNSVTPATSAAPSPAPASEKGEDKDKDSEKEKD--------KTSA 1588
            .:|..:||.....:                        :.|.:|.|:..:|:|        |...
 Frog   904 KIARYKAPFHQLRI------------------------QYGTNKGKNYTEEEDRFLICMLHKMGF 944

  Fly  1589 EKSEVKQE-----QEAEEDKKPGDVKQENPVEEAAGDTKPSDAEVKTEVAKTEPKEETKDPEVKE 1648
            :|..|.:|     :.|.:.:....:|....:|        ......|.::..| ||..   |::|
 Frog   945 DKENVYEELRQCVRNAPQFRFDWFIKSRTAME--------LQRRCNTLISLIE-KENL---EIEE 997

  Fly  1649 EPKTEEKEKEKVDDKKPIPPTTVIDDDDDDVMIVKEDGELEKPSASSPKDQK 1700
            :.:.|:|:::    .||.|.....|       :|        |.:|..||.|
 Frog   998 KERAEKKKRQ----PKPQPSKRKAD-------VV--------PDSSGKKDAK 1030

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mi-2	NP_001014591.1	CHDNT	138..190	CDD:285335
		PHD1_CHD_II	380..422	CDD:277006
		PHD2_CHD_II	440..482	CDD:277007
		CHROMO	490..558	CDD:237991
		CHROMO	615..667	CDD:214605
		SNF2_N	734..1028	CDD:278600	123/297 (41%)
		DEXDc	751..907	CDD:238005	60/156 (38%)
		Helicase_C	1053..1167	CDD:278689	68/113 (60%)
		DUF1087	<1292..1337	CDD:283996	8/56 (14%)
		DUF1086	1380..1517	CDD:283992	23/142 (16%)
		CHDCT2	1756..1927	CDD:285336
smarca1	XP_002931866.2	PLN03142	64..1027	CDD:215601	315/1087 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000