DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Usp32 and UBP5

DIOPT Version :9

Sequence 1:	NP_001262074.2	Gene:	Usp32 / 40169	FlyBaseID:	FBgn0036913	Length:	1779	Species:	Drosophila melanogaster
Sequence 2:	NP_001323724.1	Gene:	UBP5 / 818691	AraportID:	AT2G40930	Length:	924	Species:	Arabidopsis thaliana

Alignment Length:	1440	Identity:	319/1440 - (22%)
Similarity:	465/1440 - (32%)	Gaps:	629/1440 - (43%)

- Green bases have known domain annotations that are detailed below.

  Fly   391 LRREERRPY------------RVGQFWYLITHDWWLSWMQYTQHTTHTCDYCKRTASQRTAVDEA 443
            |..||.|.:            :.|..:||||..||..|::|...
plant    15 LSPEEERVFIRDIAIAAEANSKEGDTFYLITQRWWQEWIEYVNQ--------------------- 58

  Fly   444 LVCDESFNTH---SLEQHDSYSLGSGTGSASGSGSASSGISAGRHCGPVRPGPIDNSNLI----- 500
               |:..||:   ||.:|.. |.||.|..                    :|..||||:||
plant    59 ---DQPCNTNDGSSLSEHCD-SPGSSTLK--------------------KPSRIDNSDLIYDSSL 99

  Fly   501 --TANPFRNVRTLTGEGGHLKRDTPLVQNHDFELVPKSLWKALNRWYGDNLPLPRQVIQPPNSDV 563
              .:|....:.||.             :..|:.|:|:.:|..|..|||....|.|:||....|..
plant   100 EDPSNTSEIIETLQ-------------EGRDYVLLPQEVWNQLRSWYGGGPTLARRVISSGLSQT 151

  Fly   564 EL--ELYPLNLRILLHQAQPSQTGVGGGTQLGSWGSTVSGGYGVLASGGGYAAIAVSSVLQPPKR 626
            ||  |:|||.|::||   .|.                           ..::||.:
plant   152 ELAVEVYPLRLQLLL---MPK---------------------------SDHSAIRI--------- 177

  Fly   627 YLAYTAAFSRLATVRQVGEFLCEQLRLKSEDIRLWHV-------------PQLDNGAILLEEDAM 678
                    |:..|:|::....||...|.||.:|:|..             ..||:..:.:::|.:
plant   178 --------SKKETIRELHRRACEIFDLDSEHVRIWDYYGHQKYSLMNDLDKTLDDANLQMDQDIL 234

  Fly   679 ----------------CLKE--LLIRDNDQLLLEIRNKDLTWPEELGSLATAQCGQGAGTPGDRR 725
                            ..:|  |:..|:..:|:|        |.: .|||      .||.....|
plant   235 VEVLDINGTLSSAHIQSAQENGLVDGDSTSILIE--------PSK-SSLA------AAGGFSSSR 284

  Fly   726 RLTRSSIMSV-----------------HAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREM 773
            ...|:..:.|                 ...|.|||.|||||||||:|:|.|.:|...|.|||.:.
plant   285 NAFRTGSVEVSQSFDNTYSSTGVTTRGSTAGLTGLLNLGNTCFMNSAIQCLVHTPEFASYFQEDY 349

  Fly   774 HRFEVNAANKLGTKGQLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLE 838
            |: |:|..|.||..|:||:.:.:||:::|......:||...:..:.::||||:|..||||||||.
plant   350 HQ-EINWQNPLGMVGELALAFGDLLRKLWAPGRTPIAPRPFKAKLARFAPQFSGYNQHDSQELLA 413

  Fly   839 WLLDALHEDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGC 903
            :|||.||||||||..|||...:|::||||:.||.|.|..|.|||.|||:|:..||.||.:.|..|
plant   414 FLLDGLHEDLNRVKHKPYINSRDADGRPDEEVADEFWKNHIARNDSIIVDVCQGQYKSTLVCPIC 478

  Fly   904 GHESVRFDPFSLLSLPLPVENYIYFEVLVILLD-GSVPIKYGFRLNSDCKYSHLKHKLSTMCSLP 967
            ...||.||||..|||||.........|.|...| .::|......::...:...|...|:..||
plant   479 NKVSVTFDPFMYLSLPLQFNTTRAITVTVFSCDKTALPSTITVNVSKQGRCRDLIQALTNACS-- 541

  Fly   968 PNLMLVCELWNSQIRQVLNDDEKLRTQSAKELYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQRSS 1032
                             |...|:|:....:..::::|.|
plant   542 -----------------LKQSEELKLAEIRNNFIHRLFE-------------------------- 563

  Fly  1033 ALITSAQDSLSSLSTLQTSSHRASSRVLCNGHVSGL---------DVEGEAEVGTDVSQCNSNSN 1088
                   |.|..||:::...|.|:.::..:...:.|         ...||.|....:..|.:
plant   564 -------DPLIPLSSIKDDDHLAAYKLSKSSENTTLLRLVLRRRDQKAGERESTVQLKPCGT--- 618

  Fly  1089 YNPIVSTYS-GNGSGDNQVHELLPDEAGKVSRCFGKRECMPHSLFCFKESLILSSSPENTFMHGA 1152
              |::|:.| |:.....::|.|:.:....    |.:.|.:.      |:....||.||.
plant   619 --PLLSSASCGDALTKGKIHCLVQNMLSP----FRREESVG------KKGNSDSSIPER------ 665

  Fly  1153 AAQQKRVSSAKLLHTESNTSSMSYTNHSGENSMESSLTEPIPLADLEPVSSRNGSGGEDCSYRTS 1217
                   .||:..:||                      |...:..|:.....|.|
plant   666 -------RSARFNNTE----------------------EEDKVGGLKKAKKSNSS---------- 691

  Fly  1218 PNDSSGLSTGHTLGA---SLD-VDEQAEEGNAEDHDQPDQITTSQPETSSGVYSRRSSQPPHKAG 1278
                       .|||   ||. :||             |..|.:.|:..:......||.
plant   692 -----------DLGASKLSLQLIDE-------------DNKTINLPDNEAEAMKLPSSA------ 726

  Fly  1279 KYLVAVHRKITRHDSYFLSYHKTRPSLFGVPLLIPNSEGGTHKDLYCAVWLQVSRLLSPLPATTE 1343
              .|.::...|             |.|.|:
plant   727 --TVTIYLDWT-------------PELSGM----------------------------------- 741

  Fly  1344 QANHAADCDDSLGYDFPFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASN 1408
                         ||            :||
plant   742 -------------YD------------ITC----------------------------------- 746

  Fly  1409 TSTPKMNAKFPSLPNLEAKRTPEYTASLSYTPTTKYFEDFTIAIDWDPTALHLRYQSTLERLWVD 1473
                     ..|||.:           |.|.||||
plant   747 ---------LESLPEV-----------LKYGPTTK------------------------------ 761

  Fly  1474 HETIAISRREQVEPVDLNHCLRAFTSEEKL---EQWYHCSHCKGKKPATKKLQIWKLPPILIVHL 1535
                    :.:.||:.|..||.||..||.|   |.|: |..|..::.|:|||.:|:||.:|::||
plant   762 --------KARSEPLSLYACLEAFLREEPLVPDEMWF-CPQCNERRQASKKLDLWRLPEVLVIHL 817

  Fly  1536 KRFNCVNGKWVKSQKVVHFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNEVVSELD 1600
            |||:.......|.:..|:||..|.|.|.|:|:
plant   818 KRFSYSRSMKHKLETFVNFPIHDLDLTKYVAN--------------------------------- 849

  Fly  1601 EIDAPSKEVKEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVDGEFEDY 1665
                                                  ||..:.|
plant   850 --------------------------------------KNLSQPQ-------------------- 856

  Fly  1666 HQHRLKPDVDQFDPRYRLYAVVSHSGMLNGGHYISYASNATGS-WYCYNDSSCREISQKPVIDPS 1729
                          .|.|||:.:|.|.:..|||.::......| ||.::||....|::..| ...
plant   857 --------------LYELYALTNHYGGMGSGHYTAHIKLLDDSRWYNFDDSHISHINEDDV-KSG 906

  Fly  1730 AAYLLFYERK 1739
            |||:|||.||
plant   907 AAYVLFYRRK 916

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	169/573 (29%)
		Peptidase_C19	<1480..1737	CDD:351799	60/260 (23%)
UBP5	NP_001323724.1	UBP12	32..917	CDD:227847	315/1423 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	349	1.000	Domainoid score	I222
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	359	1.000	Inparanoid score	I591
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283205at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2807
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21646
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.070