Protein Alignment Usp32 and Usp31

DIOPT Version :9

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001028345.1
• Gene: Usp31 / 76179
• MGIID: 1923429
• Length: 1344
• Species: Mus musculus
• Alignment Length: 1211
• Identity: 233/1211 - (19%)
• Similarity: 367/1211 - (30%)
• Gaps: 513/1211 - (42%)

  Fly   581 PSQTGVGGGTQLGSWGSTV--SGGYGVLASGGGYAAIAVSSVLQPPKRYLAYTAAFSRLATVRQV 643
            |......||.:..|:...:  ||..|.....||....|.||.                 ::.|.|
Mouse     9 PGPPVAAGGKEKRSFSKRLFRSGRAGGGGGAGGPGPAAPSSP-----------------SSARSV 56

  Fly   644 GEFLCEQLRLKSEDIRLWHVPQ----LDNGAILLEEDAMCLKELLIRDNDQLLLEIRNKDLTWPE 704
            |.|:...|:..|   .|.|:..    .|.|.:     ..|..                     |.
Mouse    57 GSFMSRVLKTLS---TLSHLSSEGAAPDRGGL-----RSCFP---------------------PG 92

  Fly   705 ELGSLATAQCGQGAGTPGDRRRLTRSSIMSVHAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYF 769
            ...:.....|.....:|..      .:..|...||..||.|.||||||||.||.|.||:..|:|.
Mouse    93 PASAPTPPPCPPPPASPAP------PACASEPVPGVAGLRNHGNTCFMNATLQCLSNTELFAEYL 151

  Fly   770 QREMHRF-----EVNAANKLGT----KGQLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQF 825
            ....:|.     |..:....|.    :|::..:.|.|::.:||...........:..|:|.|.|:
Mouse   152 ALGQYRAGRPEPEPESEQPAGRGPHGQGEVTEQLAHLVRALWTLEYTPQHSRDFKSIVSKNALQY 216

  Fly   826 AGGGQHDSQELLEWLLDALHEDLNRVME-------KPYSELKDSNGRPDKIVAAEAWSQHHARNQ 883
            .|..|||:||.|.||||.:|||||..::       ||.||.......|..:.:
Mouse   217 RGNSQHDAQEFLLWLLDRVHEDLNHAVKQSGQPPLKPPSETDMMPEGPFPVCS------------ 269

  Fly   884 SIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLPLPVENY--IYFEV-------------LVI 933
            :.:.:||..|.:|.::|..|..:|..||||..:|||:|:.:.  :|..|             :.:
Mouse   270 TFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLPIPLPHTRPLYVTVVYQGKCSHCMRIGVAV 334

  Fly   934 LLDGSVPIKYGFRLNSDCKYSHLKHKLSTMCSLPPNLMLVCELWNSQIRQVLNDDEKLRTQSAKE 998
            .|.|:|              :.|:..:|....:|.:.:::.|::.....:..:|.:.|.|....:
Mouse   335 PLSGTV--------------ARLREAVSMETKIPTDQIVLTEMYYDGFHRSFSDTDDLETVHESD 385

  Fly   999 -LYVYQLPE-------QSMR-TRSNSGLSMHIEQGLKDIQRSSALITSAQDSLSSLSTLQTSSHR 1054
             ::.::.||       .|.| ...|:.|: |::.||...:.||...|:|:.....|.|     ..
Mouse   386 CIFAFETPEIFRPEGILSQRGIHLNNNLN-HLKFGLDHHRLSSPAPTAAKQGRVDLPT-----RV 444

  Fly  1055 ASSRVLCNGHVSGLDVEGEAEVGTDVSQCNSNSNYNPIVSTYSGNGSGDNQVHELLPDEAGKVSR 1119
            ||.:::                   :..||
Mouse   445 ASDKIV-------------------LLVCN----------------------------------- 455

  Fly  1120 CFGKRECMPHSLFCFKESLILSSSPENTFMHGAAAQQKRVSSAKLLHTESNTSSMSYTNHSGENS 1184
                |.|                         ...|.||.....:||.|...:
Mouse   456 ----RAC-------------------------TGQQGKRFGLPFVLHLEKTVA------------ 479

  Fly  1185 MESSLTEPIPLADLEPVSSRNGSGGEDCSYRTSPNDSSGLSTGHTLGASLDVDEQAEEGNAEDHD 1249
                       .||
Mouse   480 -----------WDL--------------------------------------------------- 482

  Fly  1250 QPDQITTSQPETSSGVYSRRSSQPPHKAGKYLVAVHRKITRHDSYFLSYHKTRPSLFGVPLLIPN 1314
                                              :.::|.....|||     ||:
Mouse   483 ----------------------------------LQKEILEKMKYFL-----RPT---------- 498

  Fly  1315 SEGGTHKDLYCAVWLQVSRLLSPLPATTEQANHAADCDDSLGYDFPFTLRAVKADGLTCAICPWS 1379
                        |.:||                   |        ||:||.|...|:|
Mouse   499 ------------VSIQV-------------------C--------PFSLRVVSVVGIT------- 517

  Fly  1380 SFCRGCEIRCNNDYVLQGALPPINAAASNTSTPKMNAKFPSLPNLEAKRTPEYTASLSYTPTTKY 1444
                         |:|.....|:              ..|::........|..||.:.
Mouse   518 -------------YLLPQEEQPL--------------CHPTVERALKSCGPGGTAHVK------- 548

  Fly  1445 FEDFTIAIDWDPTALHLRYQSTLERLWVDHETIAISRREQVEP--VDLNHCLRAFTSEEKL---E 1504
                 :.::||.......:.:|.:....|.|::.:.:.:..:|  ..|:.|.:.:|.||:|   :
Mouse   549 -----LVVEWDKETKDFLFVNTEDEYIPDAESVRLQKEQHHQPQTCTLSQCFQLYTKEERLAPDD 608

  Fly  1505 QWYHCSHCKGKKPATKKLQIWKLPPILIVHLKRFNCVNGKWVKSQKVVHFPFDDFDPTPYLASVP 1569
            .| .|.|||..:..:..|.:|.||.:||:|||||.....:.:|.|.:|.||....|.||::....
Mouse   609 AW-RCPHCKQLQQGSITLSLWTLPDVLIIHLKRFRQEGDRRMKLQNMVKFPLTGLDMTPHVVKRS 672

  Fly  1570 QETILRHKELLELKNDAEMTMATNEVVSELDEIDAPSKEVKEELPNQTGSTKATASPPPTGNILR 1634
            |.:                                      ..||:.....:.     |.|
Mouse   673 QSS--------------------------------------WSLPSHWSPWRR-----PYG---- 690

  Fly  1635 QSKTKNAVRRQRLISTSLTKTPIVDGEFEDYHQHRLKPDVDQFDPRYRLYAVVSHSGMLNGGHYI 1699
                             |.:.|      |||              .|.||||.:|.|.:.||||.
Mouse   691 -----------------LGRDP------EDY--------------IYDLYAVCNHHGTMQGGHYT 718

  Fly  1700 SYASNAT-GSWYCYNDSSCREISQKPVIDPSAAYLLFYERK 1739
            :|..|:. |.|||::||..:::|:..|. ...||:|||:|:
Mouse   719 AYCKNSVDGLWYCFDDSDVQQLSEDEVC-TQTAYILFYQRR 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	107/458 (23%)
		Peptidase_C19	<1480..1737	CDD:351799	66/262 (25%)
Usp31	NP_001028345.1	Peptidase_C19	<119..>244	CDD:271592	48/124 (39%)
		Peptidase_C19	124..>329	CDD:271592	68/216 (31%)
		Peptidase_C19R	<589..756	CDD:239139	65/252 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1283205at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920