Protein Alignment Usp32 and Usp38

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_081830.2
• Gene: Usp38 / 74841
• MGIID: 1922091
• Length: 1042
• Species: Mus musculus
• Alignment Length: 679
• Identity: 138/679 - (20%)
• Similarity: 231/679 - (34%)
• Gaps: 235/679 - (34%)

  Fly   702 WPEELGSLATAQCGQGAGTPGDRRRLTRSSIMSVHAPGATGLHNLGNTCFMNAALQVLFNTQPLA 766
            |..:..:||:.              |:|.|..|  ..|.|||.||||||:||:.||.||    :|
Mouse   422 WTSQSNALASC--------------LSRLSGKS--ETGKTGLINLGNTCYMNSVLQALF----MA 466

  Fly   767 QYFQREMHRFEVNAANKLGTKGQLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQH 831
            ..|:|::....:|..|.|       |:..:.|......|.|.....::.|..:: .|.|....|.
Mouse   467 TEFRRQVLSLNLNGCNSL-------MKKLQHLFAFLAHTQREAYAPRIFFEASR-PPWFTPRSQQ 523

  Fly   832 DSQELLEWLLDALHEDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHA--------------RN 882
            |..|.|.:|||.|||      |:....::.|:...:.:..||...|...              ..
Mouse   524 DCSEYLRFLLDRLHE------EEKILRVQSSHKPSEGLDCAETCLQEVTSKVAVPTESPGTGDSE 582

  Fly   883 QSIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSL---PLP-VENYIYFEVLVI-------LLD 936
            :::|..:|.|:|::.:.||.||..|.:.:.|:.|||   |.| ||:..:.:...:       |:.
Mouse   583 KTLIEKMFGGKLRTHICCLNCGSTSHKVEAFTDLSLAFCPSPSVEDLSFQDTASLPSAQDDGLMQ 647

  Fly   937 GSV------PIKYGFRLNSDCKYSHLKHKLSTMCSLPPNLMLVCELWNSQIRQ-VLN-------- 986
            .||      |:.|.                      |.....||:   |.:.| ||.
Mouse   648 TSVADPEEEPVVYN----------------------PATAAFVCD---SVVNQRVLGSPPVEFHC 687

  Fly   987 -DDEKLRTQSAKELYVYQLPEQ-------SMRTRSNSGLSMHIEQGLKDIQ-RSSALITSAQDSL 1042
             :...:..:|||.|....:|:.       |:....|..|:..:..|..... .|.|.:.:|:.::
Mouse   688 AESSSVPEESAKILISKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTM 752

  Fly  1043 S--------SLSTLQTS---SHRASSRVLCN--------------GHVSGLDVEGEAEVG-TDVS 1081
            .        .|:.|:.|   .:....::|.|              ...|.|......:|. ||::
Mouse   753 QITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDIN 817

  Fly  1082 QCNSNSNYNPIVSTYSGNGSGDNQ---------------VHELLPDEAG-------KVSRCFGKR 1124
            : |......|         ||..:               ||..:..|:|       .::......
Mouse   818 E-NLPKKLKP---------SGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSY 872

  Fly  1125 ECMPHSLFCFKESLILSSSPENTFMHGAAA---------QQKRVSSAKLLHTESNTSSMSYTNHS 1180
            :..|.|     |||.|  :|..:.:.|..:         :.|.:|....|..:|..:..|:.:
Mouse   873 QMCPQS-----ESLAL--APSQSCLLGVESPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQS-- 928

  Fly  1181 GENSMESSLTEPIPLADLEPVSSRNGSGGEDCSYRTSPNDSSGLSTGHTLGASLDVDEQAEEGNA 1245
                             ::.::||            .|.|     |.:.|     :.::....|.
Mouse   929 -----------------VQKITSR------------FPKD-----TAYVL-----LYKKQSRANG 954

  Fly  1246 EDHDQPDQITTSQPETSSGVYSRRSSQPP 1274
            .|.|.|          :|||::  :..||
Mouse   955 IDSDNP----------ASGVWA--NGDPP 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	84/340 (25%)
		Peptidase_C19	<1480..1737	CDD:470612
Usp38	NP_081830.2	Peptidase_C19H	446..947	CDD:239129	120/601 (20%)