DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Usp32 and usp3

DIOPT Version :10

Sequence 1:NP_001262074.2 Gene:Usp32 / 40169 FlyBaseID:FBgn0036913 Length:1779 Species:Drosophila melanogaster
Sequence 2:NP_001186800.1 Gene:usp3 / 569679 ZFINID:ZDB-GENE-030131-5142 Length:524 Species:Danio rerio


Alignment Length:414 Identity:105/414 - (25%)
Similarity:164/414 - (39%) Gaps:112/414 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   649 EQLRLKSEDIRLWHVPQLDNGAILLEEDAMCLK--ELLIRDNDQLLLEIRNKDLTWPEELGSLAT 711
            |:||.|.:.    |...:|..:.    ...|.|  |.::  ||..|..::..    .|.|.||..
Zfish    77 EKLREKGQQ----HSVCMDCNSY----STFCYKCDEFVV--NDTKLGHVQRV----REHLQSLEN 127

  Fly   712 AQCGQGAGTPGDRRR-----LTRSSIMSVHAPG-----ATGLHNLGNTCFMNAALQVLFNTQPLA 766
            :.|    .|...|:|     .:..|.|...:.|     ||||.||||||||||.||.|.|.|..:
Zfish   128 SVC----NTDRQRKRKMSESFSPDSKMKQDSEGALVQCATGLRNLGNTCFMNAILQSLSNIQVFS 188

  Fly   767 QYFQREMHRFEVNAANKLG-----TKGQ------LAMRYAELLKEVWTATTRSVAPLKLRFCVNK 820
            .|| :|:....:.:....|     |:.|      |...:.:.|..:|..:..:.:|..|.:.:.|
Zfish   189 CYF-KELPSVALRSGKTAGRRMYHTRSQGDSSVSLVEEFRKTLCSLWQGSQTAFSPDALFYVIWK 252

  Fly   821 YAPQFAGGGQHDSQELLEWLLDALHEDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHAR---- 881
            ..|.|.|..|.|:.|.|.:|||.||.::.          .:.||.|...|.::  ..:||.    
Zfish   253 IMPSFRGYQQQDAHEFLRYLLDHLHREMQ----------GNKNGSPSPPVTSD--EPNHASESKC 305

  Fly   882 ----NQSIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLPLPVENYIYFEVLVILLDGSVPIK 942
                ..:|:..:|.|.|:::|.||.||.||.:||||..|||.:|.:                   
Zfish   306 FINGTSTIVTSVFGGVLQNEVYCLICGTESRKFDPFLDLSLDIPNQ------------------- 351

  Fly   943 YGFRLNS--------DCKYSHLKHKLSTMCSLPPNLMLVCELWNSQIRQVLNDDEKLRTQSAKEL 999
              ||:.:        .|..|......:.:..|....:.:|...            |.|.:|.|:.
Zfish   352 --FRIKTTKDQEPGPTCTLSDCLRSFTDLEELDETELYMCHKC------------KKRQKSTKKF 402

  Fly  1000 YVYQLPEQSMRTRSNSGLSMHIEQ 1023
            ::.:||:.         |.:|:::
Zfish   403 WIQKLPKV---------LCLHLKR 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Usp32NP_001262074.2 EFh_PI-PLC 198..>251 CDD:333715
EF-hand motif 198..222 CDD:320029
EF-hand_7 227..290 CDD:463900
UBP12 486..>1002 CDD:227847 101/391 (26%)
Peptidase_C19 <1480..1737 CDD:470612
usp3NP_001186800.1 zf-UBP 29..109 CDD:460464 9/41 (22%)
UCH 163..512 CDD:425685 81/310 (26%)
Blue background indicates that the domain is not in the aligned region.

Return to query results.
Submit another query.