DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp32 and usp8

DIOPT Version :9

Sequence 1:	NP_001262074.2	Gene:	Usp32 / 40169	FlyBaseID:	FBgn0036913	Length:	1779	Species:	Drosophila melanogaster
Sequence 2:	XP_009291628.1	Gene:	usp8 / 565434	ZFINID:	ZDB-GENE-030131-1949	Length:	1067	Species:	Danio rerio

Alignment Length:	333	Identity:	106/333 - (31%)
Similarity:	162/333 - (48%)	Gaps:	36/333 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   686 RDNDQLLLEIRNKDLTWPEELGSLATAQCGQGAGTPGDRR-------------RLTRSSIMSV-- 735
            |:..:|.....:.|::  :|| |..|.|  :.|..|...|             .:||.|...:
Zfish   663 REQSKLKRSYSSPDIS--QEL-SAETRQ--RPAAVPSINRENKPLAASTYAKVEITRPSAAKIRN 722

  Fly   736 -------HAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANKLGTKGQLAMR 793
                   ..|..|||.||||||:||:.||.|.||..:|.||.|..::.::|.||.||.||::|..
Zfish   723 LNPVFGGQGPLLTGLRNLGNTCYMNSILQCLCNTVAMADYFNRNYYQDDINRANILGHKGEVAEE 787

  Fly   794 YAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHEDLNRV-MEKPYS 857
            ::.::|.:|....:.::||..:..:.|...:|:.....||||||.:|:|.||||||:. ..:.|.
Zfish   788 FSVVMKALWLGQYKMISPLDFKGTICKINSRFSSYEHQDSQELLLFLMDGLHEDLNKADKRRGYK 852

  Fly   858 ELKDSNGRPDKIVAAE-AWSQHHARNQSIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLPLP 921
            |  :.....|.:.||: |||:|...|:|||:.||.||.||.|.|:.|.|:|..|:.|..|:|.:.
Zfish   853 E--EEIEHLDDVSAADLAWSKHKQLNESIIVALFQGQFKSTVQCMSCQHKSRTFETFMYLTLEMT 915

  Fly   922 VENYIYFEVLVILLDGSVPIKYGFRLN-SDCKYSHLKHKLSTMCSLPPNLMLVCELWNSQIRQVL 985
            ..:....:..:.|......:..|.|.. ..||......|...:..|||.|::..:.:..:.|.
Zfish   916 ASSKCSLQDCLKLFHKEERLTDGNRFYCRHCKTHRDAIKRMQIWKLPPILLVHLKRFKYEGRW-- 978

  Fly   986 NDDEKLRT 993
              .|||:|
Zfish   979 --REKLQT 984

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	106/333 (32%)
		Peptidase_C19	<1480..1737	CDD:351799
usp8	XP_009291628.1	USP8_dimer	8..115	CDD:312504
		RHOD	175..306	CDD:320771
		Atrophin-1	<316..644	CDD:331285
		UCH	735..1064	CDD:306860	91/256 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000