Protein Alignment Usp32 and usp31

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: XP_005164285.1
• Gene: usp31 / 564487
• ZFINID: ZDB-GENE-100210-4
• Length: 1303
• Species: Danio rerio
• Alignment Length: 1171
• Identity: 230/1171 - (19%)
• Similarity: 369/1171 - (31%)
• Gaps: 488/1171 - (41%)

  Fly   617 VSSVLQPPKRYLAYTAAFSRLATVRQVGEFLCEQLRLKSEDIRLWHVPQLDNGAILLEEDAMCLK 681
            :||.....::...::....|..:||.||.|:...|:..|   .|.|.     |:.|...|.
Zfish     1 MSSKSSSKEKKSGFSKKLFRRGSVRSVGSFMSRVLKTLS---TLSHF-----GSELHAPDG---- 53

  Fly   682 ELLIRDNDQLLLEIRNKDLTWPEELGSLAT--AQCGQGAGTPGDRRRLTRSSIMSVHAPGATGLH 744
                ..:|......:|      |..||:|:  :.||         ..|:|..|     ||..||.
Zfish    54 ----EKDDGGFTSFKN------EGKGSVASDESDCG---------GFLSRDKI-----PGVAGLK 94

  Fly   745 NLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANKLGTKGQLAMRYAE-----------LL 798
            |.||||||||.||.|.||:..|:|...|.:|.:.....|..|.|.:..:.|:           |:
Zfish    95 NHGNTCFMNAILQCLSNTELFAEYLALEQYRGDQTDDEKPKTNGVVGRKGAQDRGEVTEQLSGLV 159

  Fly   799 KEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHEDLNRVME-------KPY 856
            :.:||...........:..|::.|.|:.|..|||:||.|.||||.:|||||.::.       ||.
Zfish   160 RALWTFEYTPQHSRDFKNAVSRSAMQYRGNAQHDAQEFLLWLLDRVHEDLNHLVHPNIRGSVKPP 224

  Fly   857 SELKDS--NGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLP 919
            :|..|:  .|....:.|.           |.:.:||..|.:|.::|..|..:|..||||..:|||
Zfish   225 TEEDDAALEGPSPPLSAG-----------SFVQELFQAQYRSSLTCPHCQKQSNTFDPFLCISLP 278

  Fly   920 LPVENY--IYFEVLVILLDG--SVPIKYGFRLNSDCKYSHLKHKLSTMCSLPPNLMLVCELWNSQ 980
            :|:.:.  :|   :.::..|  |..::.|..:..:...|.|:..:|....:||:..::.|::...
Zfish   279 IPLPHTRPLY---VTVVYQGKYSHCMRIGVAVPLNSTVSRLREAVSRETKIPPDQFVLTEMYYDG 340

  Fly   981 I-RQVLNDDEKLR-TQSAKELYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQRSSALITSAQDSLS 1043
            . |...:||:.|. .|.:..::.::.||
Zfish   341 FHRSFCDDDDDLDIIQESDSVFAFETPE------------------------------------- 368

  Fly  1044 SLSTLQTSSHRASSRVLCNGHVSGLDVEGEAEVGTDVSQCNSNSNYNPIVSTYSGNGSGDNQVHE 1108
               |.:..:.|:
Zfish   369 ---TFRLENIRS----------------------------------------------------- 377

  Fly  1109 LLPDEAGKVSRCFGKRECMPHSLFCFKESLILSSSPENTFMHGAAAQQKRVSSAKLLHTESNTSS 1173
                                      |...:|::..:|...:||
Zfish   378 --------------------------KRGSLLANLNQNNLKYGA--------------------- 395

  Fly  1174 MSYTNHSGENSMESSLTEPIPLADLEPVSSRNGSGGED-----CSYRTSPNDSSGLSTGHTLGAS 1233
                        |||.|.......:.|.|....:|.|.     |         :...|||
Zfish   396 ------------ESSRTPSFMQGAVNPASPNKNTGSEKMILLIC---------NRACTGH----- 434

  Fly  1234 LDVDEQAEEGNAEDHDQPDQITTSQPETSSGVYSRRSSQPPHKAGKYLVAVHRKIT----RHDSY 1294
                                            ..||...|      :::.:.|.:|    :.:..
Zfish   435 --------------------------------QGRRFGLP------FVLYLERSVTWDVLQKEIL 461

  Fly  1295 FLSYHKTRPSLFGVPLLIPNSEGGTHKDLYCAVWLQVSRLLSPLPATTEQANHAADCDDSLGYDF 1359
            ....|.|||                      .|::|:.
Zfish   462 EKMRHLTRP----------------------GVYVQIG--------------------------- 477

  Fly  1360 PFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASNTSTPKMNAKFPSL--- 1421
            ||:||.|...|:|                    |:|.....|:       ..|.:...:.|.
Zfish   478 PFSLRVVGVVGIT--------------------YLLPQEEQPL-------CHPTVERAYKSCGPG 515

  Fly  1422 --PNLEAKRTPEYTASLSYTPTTKYFEDFTIAIDWDPTALHLRYQSTLERLWVDHETIAISRREQ 1484
              |:::                        |.::||.......:..|.|....|.|::.:.|.:.
Zfish   516 GPPHVK------------------------IVVEWDKETKEYLFGHTEEEYIPDAESVYLHREQH 556

  Fly  1485 VEP--VDLNHCLRAFTSEEKL---EQWYHCSHCKGKKPATKKLQIWKLPPILIVHLKRFNCVNGK 1544
            .:|  ..|..|.:.:|.||:|   :.| .|.||:..:....||.:|.||.:||:|||||.....:
Zfish   557 HQPQACTLAQCFQLYTKEEQLAPDDAW-RCPHCRQLQQGRIKLSLWTLPDVLILHLKRFRQEGDR 620

  Fly  1545 WVKSQKVVHFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNEVVSELDEIDAPSKEV 1609
            .||.|.:|.||....|..|::....|.:
Zfish   621 RVKMQNMVRFPLLGMDMAPHVVKRSQSS------------------------------------- 648

  Fly  1610 KEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVDGEFEDYHQHRLKPDV 1674
             ..||:.....:.     |.|                     |.:.|      :||
Zfish   649 -WSLPSHWSPWRR-----PYG---------------------LGRNP------DDY--------- 671

  Fly  1675 DQFDPRYRLYAVVSHSGMLNGGHYISYASNA-TGSWYCYNDSSCREISQKPVIDPSAAYLLFYER 1738
                 .|.||||.:|.|.::||||.:|..|: .|.|||::||..:.::.:.|.. ..||:|||:|
Zfish   672 -----LYDLYAVCNHHGNMHGGHYTAYCKNSIDGQWYCFDDSEVQPVADEDVCQ-QTAYILFYQR 730

  Fly  1739 K 1739
            :
Zfish   731 R 731

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	111/412 (27%)
		Peptidase_C19	<1480..1737	CDD:470612	65/262 (25%)
usp31	XP_005164285.1	UBP12	<82..732	CDD:227847	207/1059 (20%)
		PTZ00108	<931..1134	CDD:240271