Protein Alignment Usp32 and usp45

DIOPT Version :9

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: XP_005158432.1
• Gene: usp45 / 564004
• ZFINID: ZDB-GENE-100211-2
• Length: 803
• Species: Danio rerio
• Alignment Length: 1140
• Identity: 207/1140 - (18%)
• Similarity: 316/1140 - (27%)
• Gaps: 549/1140 - (48%)

  Fly   679 CLKELLIRDNDQLLLEIRNKDLTWPEELGSLATAQCGQGAGTPGDRRRLT------------RSS 731
            |.:||....|.:.|.:    .|.:.::..:.||      :||.....:|.            :|.
Zfish   129 CKEELSTHCNKKALAQ----TLDFLQKQSAKAT------SGTSSKLIKLREEPAEYVDTQRGKSP 183

  Fly   732 IMSVHAPGATGLHNLGNTCFMNAALQVLFNT---QPLAQYFQREMHRFEVNAANKLGTKGQLAMR 793
            :.|...| ..|::|||||||.||.:|.|..|   ..|.|..:.:.|:.:::.:.:... |.|.:.
Zfish   184 VNSTLIP-VKGINNLGNTCFFNAVMQNLSQTHMLNDLIQDVKEKGHKMKISPSTETNL-GSLTVT 246

  Fly   794 -------------YAELLKEVWTATTRSVAPLKLRFCVNKY---APQFAGGGQHDSQELLEWLLD 842
                         :.:.:||      ....|:..:...|:.   ||:|.|..|.||||||.:|||
Zfish   247 LPSPEPLTSAMFLFLQSMKE------SGKGPVSPKILFNQLCQKAPRFKGYQQQDSQELLHYLLD 305

  Fly   843 ALH-EDLNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQ-----SIIIDLFYGQLKSKVSCL 901
            ::. |:..|:..   ..||..|...:|....|...|..|..:     :.:..:|.|:|.|.:.|.
Zfish   306 SMRVEETKRIKA---GILKAFNNPTEKTADEETKRQVKAYGKEGVKLNFVDRIFVGELTSTIMCE 367

  Fly   902 GCGHESVRFDPFSLLSLPLPVENYIYFEVLVILLDGSVPIKYGFRLNSDCKYSHLKHKLSTMCSL 966
            .|.|.|...:.|..:|||: :|..|                                      |.
Zfish   368 ECEHISTVKEAFIDISLPI-IEERI--------------------------------------SK 393

  Fly   967 PPNLMLVCELWNSQIRQVLNDDEKLRTQSAKELYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQRS 1031
            |.|                                   |.:    ...||             |.
Zfish   394 PTN-----------------------------------PAR----LGKSG-------------RE 406

  Fly  1032 SALITSAQDSLSSLSTLQTSSHRASSRVLCNGHVSGLDVEGEAEVGTDVSQCNSNSNYNPIVSTY 1096
            ...:||..|||::                   |                ||.|.||
Zfish   407 QDSLTSHDDSLAA-------------------H----------------SQANRNS--------- 427

  Fly  1097 SGNGSGDNQVHELLPDEAGKVSRCFGKRECMPHSLFCFKESLILSSSPENTFMHGAAAQQKRVSS 1161
                                                                        :|:|.
Zfish   428 ------------------------------------------------------------RRLSG 432

  Fly  1162 AKLLHTESNTSSMSYTNHSGENSMESSLTEPIPLADLEPVSSRNGSGGEDCSYRTSPNDSSGLST 1226
            .||....|:||.    :..|.:::.|...|.:.:|         |.|..  ||||.
Zfish   433 QKLQSRHSSTSH----DDRGPDTVSSRQEEDLCVA---------GRGLS--SYRTD--------- 473

  Fly  1227 GHTLGASLDVDEQAEEGNAEDHDQPDQITTSQPETSSGVYSRRSSQPPHKAGKYLVAVHRKITRH 1291
              |:|:..|..|  :|.|.:|.........|:.|.|..:.|  .|.....:.|..:......|.|
Zfish   474 --TMGSQSDCSE--KESNLQDSSNDADSEASESEWSPRIPS--VSSHSSTSDKTSITTTLSTTTH 532

  Fly  1292 DSYFLSYHKTRPSLFGVPLLIPNSEGGTHKDLYCAV----WLQVSRLLSPLPATTEQANHAADCD 1352
            :...    |:.||...:|.:.| .:||..:.|..||    .:..|....|:..:.|:.:...|.|
Zfish   533 NPSL----KSNPSSTPLPSIRP-QQGGAVEQLVSAVSKLGLVHTSTDTLPISHSQEELSETRDRD 592

  Fly  1353 DSLGYDFPFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASNTSTPKMNAK 1417
                                               |.::    |||
Zfish   593 -----------------------------------RQHH----QGA------------------- 599

  Fly  1418 FPSLPNLEAKRTPEYTASLSYTPTTKYFEDFTIAIDWDPTALHLRYQSTLERLWVDHETIAISRR 1482
            |..|.:             ||||::|
Zfish   600 FQVLCH-------------SYTPSSK--------------------------------------- 612

  Fly  1483 EQVEPVDLNHCLRAFTSEEKL--EQWYHCSHCKGKK----------------PATKKLQIWKLPP 1529
                ...:..||..|||.|.|  .....|.:|..::                .|.|::.|..|||
Zfish   613 ----ECSVQSCLHQFTSIELLMGNNKLLCENCTDRRQRQMKRSDKKAEKVYTSARKQMLISALPP 673

  Fly  1530 ILIVHLKRFNCVNGKWVKSQKVVHFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNE 1594
            ::.:|||||:.......|..:.|.||.                      ||:|   |....||
Zfish   674 VVTLHLKRFHQAGMNLRKVNRHVDFPL----------------------LLDL---APFCSAT-- 711

  Fly  1595 VVSELDEIDAPSKEVKEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVD 1659
                                                       .||....:|::
Zfish   712 -------------------------------------------CKNLGSGERVL----------- 722

  Fly  1660 GEFEDYHQHRLKPDVDQFDPRYRLYAVVSHSGMLNGGHYISYASNAT------------------ 1706
                                 |.||.:|.|||.:.||||.:|....|
Zfish   723 ---------------------YSLYGIVEHSGSMRGGHYAAYVKVRTPQRKPEQRRNQSGSREAC 766

  Fly  1707 ----GSWYCYNDSSCREISQKPVIDPSAAYLLFYE 1737
                |.|...:|::.:.:.:..|:: |.|||||||
Zfish   767 SAPQGQWVYVSDTTVQTVPESRVLN-SQAYLLFYE 800

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	76/359 (21%)
		Peptidase_C19	<1480..1737	CDD:351799	56/296 (19%)
usp45	XP_005158432.1	UBP14	16..>329	CDD:227532	55/220 (25%)
		UBP12	<193..800	CDD:227847	191/1063 (18%)
		Peptidase_C19	193..>389	CDD:351799	57/206 (28%)
		Peptidase_C19K	<606..800	CDD:239132	61/339 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910