Protein Alignment Usp32 and usp33

DIOPT Version :9

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001016228.1
• Gene: usp33 / 548982
• XenbaseID: XB-GENE-1016674
• Length: 892
• Species: Xenopus tropicalis
• Alignment Length: 1176
• Identity: 207/1176 - (17%)
• Similarity: 307/1176 - (26%)
• Gaps: 599/1176 - (50%)

  Fly   640 VRQVGEFLCEQLRLKS----EDIR-----LW---------------HVPQLDNGAILLEEDAMCL 680
            :..|||...|:|..||    :|.|     ||               ||   |:..:..::...||
 Frog    11 LESVGEVTKEELIKKSHGSCQDCRVRGPNLWACLENGCSYVGCGESHV---DHSTLHSQDTKHCL 72

  Fly   681 KELLIRDNDQLLLEIR------NKDLTWPEELGSLATAQCGQGAGTPGDRRRLTRSSIMSVHAP- 738
                    ...|..:|      :|::....:|.:..|:...|.:.|...:    .||.:::..|
 Frog    73 --------TVNLTTLRVWCYTCSKEVFLDRKLSTQPTSAKLQDSHTQESK----MSSSLTLKIPA 125

  Fly   739 --------------------GATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANK 783
                                |.|||.|:||||:||||||.|.|..||..||      .:.....:
 Frog   126 AVVSENLDIELEEEDELKTRGLTGLKNIGNTCYMNAALQALSNCPPLTHYF------LDCGGLAR 184

  Fly   784 LGTKGQLAMRYAELLKEVWTATTRS-VAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHED 847
            ...|..|...|.:|:.::|...... |.|..|...:....|.|.|..|.|:||.|..|:|.|||
 Frog   185 TDKKPALCKSYQKLMSDIWHKNRPGFVIPTNLFQGIKSVNPTFRGYSQQDAQEFLRCLMDVLHE- 248

  Fly   848 LNRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGCGHESVRFDP 912
                      |||:
 Frog   249 ----------ELKE--------------------------------------------------- 252

  Fly   913 FSLLSLPLPVENYIYFEVLVILLDGSVPIKYGFRLNSDCKYSHLKHKLSTMCSLPPNLMLVCELW 977
                                                                             
 Frog   253 ----------------------------------------------------------------- 252

  Fly   978 NSQIRQVLNDDEKLRTQSAKELYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQRSSALITSAQDSL 1042
                 |::..:|..:|...:|
 Frog   253 -----QIVEVEEDAQTGIVEE-------------------------------------------- 268

  Fly  1043 SSLSTLQTSSHRASSRVLCNGHVSGLDVEGEAEVGTDVSQCNSNSNYNPIVSTYSGNGSGDNQVH 1107
                                    .|| |.:::...|...|:|.|:
 Frog   269 ------------------------NLD-EDKSQSDNDFHSCDSGSS------------------- 289

  Fly  1108 ELLPDEAGKVSRCFGKRECMPHSLFCFKESLILSSSPENTFMHGAAAQQKRVSSAKLLHTESNTS 1172
               .|.|...||...:.         ..||.:|        :|   ..||.|...|....|...|
 Frog   290 ---SDHAESESRKLSEE---------LTESTML--------IH---EDQKDVEICKTWQKEKKFS 331

  Fly  1173 SMSYTNH---SGENSMESSLTEPIPLADLEPVSSRNGSGGEDCSYRTSPNDSSGLSTGHTLGASL 1234
            :....||   ..|.:::|::.|...|.. |.|..:..|...|.:...:.||
 Frog   332 NNLNQNHFLQDFEKNIQSTIEESECLKQ-ETVKVQIQSKAADFTAEVNMND-------------- 381

  Fly  1235 DVDEQAEEGNAEDHDQPDQITTSQ-PETSSGVYSRRSSQPPHKAGKYLVAVHRKI-------TRH 1291
                               :.||| |..:.|..:..||.|| |.|..... |:|:       .|.
 Frog   382 -------------------LPTSQTPLLNEGATTHLSSSPP-KPGAVWTG-HKKVPGLCPAKKRK 425

  Fly  1292 DSYFLSYHKTRPSLFGVPLLIPNSEGGTHKDLYC------AVWLQVSRLLS-PLPATTEQAN-HA 1348
            ..   .||.....:|         :|.....:.|      :|.|:..:.|| |:|...:.|. |:
 Frog   426 QK---KYHSVIADIF---------DGTIVSSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHS 478

  Fly  1349 ADCDDSLGYDFPFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASNTSTPK 1413
            :....||          |||..                  |...|..||.:
 Frog   479 SSHQSSL----------VKAGS------------------CGEAYAPQGWI-------------- 501

  Fly  1414 MNAKFPSLPNLEAKRTPEYTASLSYTPTTKYFEDFTIAIDWDPTALHLRYQSTLERLWVDHETIA 1478
              |.|                       .:||:.:.    |.||
 Frog   502 --AFF-----------------------LEYFKSWF----WGPT--------------------- 516

  Fly  1479 ISRREQVEPVDLNHCLRAFTSEEKL--EQWYHCSHCKGKKPATKKLQIWKLPPILIVHLKRFNCV 1541
                     |.|..||.||.:.::|  :..|.|..||..:...|..::.|.|.||.:|||||
 Frog   517 ---------VTLQDCLAAFFARDELKGDNMYSCEKCKKLRNGVKFCKVQKFPEILCIHLKRF--- 569

  Fly  1542 NGKWVKSQKV---VHFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNEVVSELDEID 1603
            ..:.:.|.|:   |.||.:..|..|:||.                                   |
 Frog   570 RHELMFSTKIGTHVSFPLEGLDLQPFLAK-----------------------------------D 599

  Fly  1604 APSKEVKEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVDGEFEDYHQH 1668
            :||:.|
 Frog   600 SPSQIV----------------------------------------------------------- 605

  Fly  1669 RLKPDVDQFDPRYRLYAVVSHSGMLNGGHYISYA-SNATGSWYCYNDSSCREISQKPVIDPSAAY 1732
                       .|.|.:|:.|.|..:.||||:|. :|....||.::|.|..|:|: ..:..:.||
 Frog   606 -----------TYDLLSVICHHGTASSGHYIAYCRNNLNNLWYEFDDQSVTEVSE-ATVQNAEAY 658

  Fly  1733 LLFYER 1738
            :|||.:
 Frog   659 VLFYRK 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	75/413 (18%)
		Peptidase_C19	<1480..1737	CDD:351799	55/262 (21%)
usp33	NP_001016228.1	zf-UBP	30..90	CDD:280334	12/70 (17%)
		UCH	147..662	CDD:278850	178/1021 (17%)
		Peptidase_C19	148..>178	CDD:271592	20/35 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..311		15/150 (10%)
		Peptidase_C19R	430..663	CDD:239139	83/451 (18%)
		DUSP	684..764	CDD:197831
		DUSP	790..871	CDD:197831

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910