DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Usp32 and Usp27x

DIOPT Version :9

Sequence 1:	NP_001262074.2	Gene:	Usp32 / 40169	FlyBaseID:	FBgn0036913	Length:	1779	Species:	Drosophila melanogaster
Sequence 2:	NP_062334.2	Gene:	Usp27x / 54651	MGIID:	1859645	Length:	438	Species:	Mus musculus

Alignment Length:	375	Identity:	91/375 - (24%)
Similarity:	140/375 - (37%)	Gaps:	94/375 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   724 RRRLTRSSIMSVHAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVNAANKLGTKG 788
            |||:..|..:     |..||.|||||||||..:|.|.:|..|..:|..:.||.|:.:....
Mouse    66 RRRIASSFTI-----GLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCEMPSPELC---- 121

  Fly   789 QLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALH-----EDL 848
             |....:.|.:|:::.......|.||...|..:|...||..|.|:.|.|...||.||     :|:
Mouse   122 -LVCEMSSLFRELYSGNPSPHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLHRHCKGDDV 185

  Fly   849 NRVMEKPYSELKDSNGRPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGCGHESVRFDPF 913
            .:|...|                      :|.  ..||..:|.|.|:|.|:|..|...|...||.
Mouse   186 GKVASNP----------------------NHC--NCIIDQIFTGGLQSDVTCQACHGVSTTIDPC 226

  Fly   914 SLLSLPLPVENYIYFEV---LVILLDGSVPIKYGFRLNSDC-----KYSHLKHKLSTMCSLPPNL 970
            ..:||.||.....::.:   ....|:|...|. |....:||     :..||.......|.
Mouse   227 WDISLDLPGSCTSFWPMSPGRESSLNGESHIP-GITTLTDCLRRFTRPEHLGSSAKIKCG----- 285

  Fly   971 MLVCELWNSQIRQVLNDDEKLRTQSAKELYVYQLP----------EQS--MRTRSNSGLSMHIEQ 1023
              .|:.:.               :|.|:|.:.:||          |.|  .|.:..:.:|..:|.
Mouse   286 --SCQSYQ---------------ESTKQLTMKKLPVVACFHFKRFEHSAKQRRKITTYISFPLEL 333

  Fly  1024 GLKDIQRSS---------ALITSAQDSLSSLSTLQTSSHRASSRVLCNGH 1064
            .:.....||         .|.|::.::.:..|.....:|:.:   |.:||
Mouse   334 DMTPFMASSKETRVNGQLQLPTNSANNENKYSLFAVVNHQGT---LESGH 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	75/290 (26%)
		Peptidase_C19	<1480..1737	CDD:351799
Usp27x	NP_062334.2	UCH	77..418	CDD:278850	86/359 (24%)
Usp27x	NP_062334.2	Peptidase_C19D	78..419	CDD:239125	86/358 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910