Protein Alignment Usp32 and usp10

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001006761.1
• Gene: usp10 / 448441
• XenbaseID: XB-GENE-966184
• Length: 805
• Species: Xenopus tropicalis
• Alignment Length: 900
• Identity: 176/900 - (19%)
• Similarity: 287/900 - (31%)
• Gaps: 346/900 - (38%)

  Fly  1021 IEQGLKD-IQRSSALITSAQDSLSSLSTLQ--------TSSHRASSRVLCNGHVSGLDVEGEAEV 1076
            ||.|::: |..|:||..:...|:||....|        :||.:.|:.||   |.:..|.     :
 Frog    72 IEFGIEEVIDHSTALPNNTDYSISSNLNPQAPEFILTCSSSPKTSNNVL---HENNFDA-----I 128

  Fly  1077 GTDVSQCNSNSNYNPIVSTYSGNGSGDNQVHELLPDEAGKVSRCFGKRECMPHSLFCFKESLILS 1141
            ....|:|        .:...|||...|.        .:|...|...|::..|...:.:.|.  :.
 Frog   129 NCQFSEC--------AIPDGSGNADSDG--------TSGTGQRERKKKKKRPPGYYSYLEG--VG 175

  Fly  1142 SSPENTFMHGAAAQQKRVSSAKLLHTESNTSSMSYTNHSGENSM---ESSLTEPIPLADLEPVSS 1203
            ..|..|.::|                        :.|.:|.||:   :..|.|.||::...|
 Frog   176 DVPSETLVNG------------------------HANSTGLNSISTDDPDLAEDIPISTTSP--- 213

  Fly  1204 RNGSGGEDCSYRTSPNDSSGLSTGHTLGASLDVDEQAEEGNAEDHDQPDQI-TTSQPETSSGVYS 1267
                  ..|:   ||::            .:|::.:|...:|..|:..|.. |..|||..|...|
 Frog   214 ------RTCN---SPDN------------FVDLNNEALSNDASMHNALDNARTAGQPEECSVTSS 257

  Fly  1268 RRSSQPPHKAGKYLVAVHRKITRHDSYFLSYHKTRPSLFGVPLLIPNSEGGTHKDLYCAVWLQVS 1332
            .:|..|                                         |:.|....:..||
 Frog   258 EQSCIP-----------------------------------------SDNGRESPVRTAV----- 276

  Fly  1333 RLLSPLPATTEQANHAADCDDSLGYDFPFTLRAVKADGLTCAICPWSSFCRGCEIRCNNDYVLQG 1397
              :.|...|        |..::||.....||.:.:                  |...:|..||
 Frog   277 --VQPFAGT--------DTTENLGVTNGQTLESSE------------------EGTASNGVVL-- 311

  Fly  1398 ALPPIN-----AAASNTSTPKMNAKFP----------SLPNLEAKRTPEYTASLSY------TPT 1441
             ||.::     |....|||.:.....|          |..:|.....|..|..::|      ||.
 Frog   312 -LPEVSSLSEEAKPEETSTAQAVVHLPGSASANPPAKSWASLFHNSKPSSTTQVAYVETKNATPV 375

  Fly  1442 TK--------YFEDFTIAIDWDPTALHLRYQSTLERLWVDHETIAISRREQVEPVD---LNHCLR 1495
            |.        ..::..:.:..||.|  ::....||.:.:.|:.:::..|..:...:   :|..|:
 Frog   376 TSPQVTEKQVEIKEGPVPVSEDPVA--IKIAELLEEVKLVHKPVSLQPRGLINKGNWCYINATLQ 438

  Fly  1496 AFTSEEKLEQWYHCS-----HCKGKKPATKKLQIWKLPPILIVHLKRFN-------CVNGKWVKS 1548
            |..:   ....||..     :.|.::|.|.       .|::...::..|       ....|....
 Frog   439 ALVA---CPPMYHLMKSIPVYTKAQRPCTS-------TPMIDSFVRLMNEFTNMPILPKAKQASG 493

  Fly  1549 QKVVH--FPFDDFDP-------TPYLASVPQE-----------TILR--HKELLELK------ND 1585
            :||:.  .|...|:|       |.:.:|:.::           .||.  |:|:|.||      ||
 Frog   494 EKVIRDIRPGAPFEPAYIYRLLTVFKSSLSEKGRQEDAEEYLGFILNGLHEEMLSLKKLLLPQND 558

  Fly  1586 AEMTMATNEVVSELDEIDAPSKEVKEELPNQTG-------------------------------- 1618
            ........:.|||.:||:...:|..:|...|.|
 Frog   559 KIHINNGPDPVSEKEEINKDEQEGSDEEWEQVGPRHKSSVTRQADFVQTPITDIFGGHMRSVVYQ 623

  Fly  1619 -STKATASPPP--------------------TGNILRQS------KTKNAV---RR--------- 1644
             |:|.:|:..|                    ...:.|:|      |||..|   ||
 Frog   624 QSSKESATLQPFFTLQLDIQSEKIRTVQDALESLVARESVQGYTTKTKQEVEICRRVTLEELPPV 688

  Fly  1645 ----------------QRLISTSLTKTPIVDGEF-EDYHQHRLKPDVDQFDPRYRLYAVVSHSG- 1691
                            |:||..  .:.| ||.|. :|.....:|..:.:....|||:|||.|.|
 Frog   689 LVLHLKRFVFEKTGGCQKLIKN--IEYP-VDLEISKDLLSPGVKSKIFKGQRTYRLFAVVYHHGN 750

  Fly  1692 MLNGGHYIS--YASNATGSWYCYNDSSCREISQKPVIDPS---AAYLLFYERKGL 1741
            ...||||.:  :.....| |...:|.:.:.|:|..|:..:   .||||:|.|..|
 Frog   751 SATGGHYTTDVFQIGLNG-WLRIDDQTVKVINQYQVVKQTVERTAYLLYYRRVDL 804

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847
		Peptidase_C19	<1480..1737	CDD:470612	80/393 (20%)
usp10	NP_001006761.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..170		8/38 (21%)
		UBP12	<423..>642	CDD:227847	40/228 (18%)
		Peptidase_C19	527..800	CDD:239072	61/276 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	561..593		9/31 (29%)