Protein Alignment Usp32 and Usp20-33

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_610943.2
• Gene: Usp20-33 / 36580
• FlyBaseID: FBgn0033916
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 162/820 - (19%)
• Similarity: 251/820 - (30%)
• Gaps: 341/820 - (41%)

  Fly   716 QGAGTPGDRRRLTRSSIMSVHAPGATGLHNLGNTCFMNAALQVLFNTQPLAQYFQR--EMHRFEV 778
            :|:||                  |..||.|:.|||:||:|||.|.|..|:..||..  ::..:..
  Fly    73 KGSGT------------------GLVGLQNIANTCYMNSALQALSNLPPMTHYFINCSDLVEYIA 119

  Fly   779 NAANKLGTKGQLAMRYAELLKEVWTAT---TRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWL 840
            ..:.:....|.||..|..|::|:|...   ...:||..:.:.:....|.|.|..|||:||.|...
  Fly   120 EQSARRCKPGGLAKSYRRLMQEIWQDVDDPKEFIAPRGILYGIRTVHPMFRGYQQHDTQEFLRCF 184

  Fly   841 LDALHEDLNR----------------VMEKPYSELKDSN-------------------------- 863
            :|.|||:|..                :.::..||..|.|
  Fly   185 MDQLHEELTEQVSMLPQTQNQPQYQSLQQQQPSETDDENDDEAAPASLSHASESEYDTCESSMSE 249

  Fly   864 -----------------------GRPD--KIVAAEAWSQHHARN------------QSIIIDLFY 891
                                   |.|:  .:...:|..||..:|            :|||.|:|.
  Fly   250 RSAEVLLKTEYFVTPCRTNGSNSGLPEGHSVQLQQAPLQHQQKNASSAEQKPIEAARSIISDVFD 314

  Fly   892 GQLKSKVSCLGCGHESVRFDPFSLLSLPLPVENYIYFEVLVILLDGSVPIKYGFRLNSDCKYSHL 956
            |:|.|.|.||.|...|.|.:.|..||||:|  |..:..||                       |.
  Fly   315 GKLLSSVQCLTCDRVSTREETFQDLSLPIP--NRDFLNVL-----------------------HQ 354

  Fly   957 KHKLSTM------CSLPPNLMLVCELWN--------------SQIRQVLNDDE------------ 989
            .|.||..      .|...|...:..:||              ..:....:.||
  Fly   355 THSLSVQSLNAAETSARTNEGWLSWMWNMLRSWIYGPSVTLYDCMASFFSADELKGDNMYSCERC 419

  Fly   990 -KLRTQSAKELYVYQLPEQSMRTRSNSGLSMHIEQGLKDIQRSSALITSA--------------Q 1039
             |||| ..|...|..|||.         |.:|:::...|:..||.:.:..              :
  Fly   420 NKLRT-GIKYSRVLTLPEV---------LCIHLKRFRNDLSYSSKISSDVYFPLEGFDMRPYIHK 474

  Fly  1040 DSLSSLSTLQTSSHRASSRVLC-NGHVSG-----------------LDVEGEAEVGTD-VSQCNS 1085
            |..|.::....||      |:| :|.|.|                 .|.:...||.:: |..|.:
  Fly   475 DCKSEVAIYNLSS------VICHHGTVGGGHYTCFARNTLNGKWYEFDDQFVTEVSSELVQSCQA 533

  Fly  1086 N---------------------SNYNPI----------------VSTYSGNGSGDNQVHELLPDE 1113
            .                     |..:|:                ::|:|..|..:||  |:|
  Fly   534 YVLFYHKHNPQMKLVRDEAMTLSTSHPLCDSDIQFYITREWLSRLATFSEPGPINNQ--EML--- 593

  Fly  1114 AGKVSRCFGKRECMPHSLFCFKESLILS------SSP-----ENTFMHGAAAQ-------QKRVS 1160
                        | ||......::.::|      |.|     ..||..|.|..       .||
  Fly   594 ------------C-PHGGILHSKADVISQIAVPISQPLWDYLYRTFGGGPAVNIIFECEICKR-- 643

  Fly  1161 SAKLLHTESNTSSMSYTNHSG-ENSMESSLTEPIPL---------------ADLEPVS------- 1202
            :|:.|..........:|.::| :|..:|:....|.:               .|..|::
  Fly   644 AAETLSRRQQYELNEFTKYNGLQNEFDSTAIYAIAMPWLRSWQQFSRGKTHKDPGPITNEGIAAP 708

  Fly  1203 SRNGS----------------------------GGEDCSYRTSPNDSSGLSTGHTLGASLDVDEQ 1239
            :.|||                            ||.:...|.:.:|.........:....:.|:.
  Fly   709 TENGSATVSCVRLGSDYAQLNARLWRFLHNIYGGGPEIILRQALSDEDDAEEIEIIDQDDECDDD 773

  Fly  1240 AE---EGNAEDHD---QPDQITTSQPETSSGVYSRRSSQP 1273
            .:   ||..||.:   ...|...|..|::.|:.:..|..|
  Fly   774 EDQDLEGEGEDEEIAAASYQHNHSDTESNLGIRNTPSPSP 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	91/402 (23%)
		Peptidase_C19	<1480..1737	CDD:470612
Usp20-33	NP_610943.2	UCH	80..538	CDD:425685	110/498 (22%)
		DUSP	560..643	CDD:197831	18/100 (18%)
		DUSP	667..755	CDD:197831	11/87 (13%)