Protein Alignment Usp32 and Usp44

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: XP_038934982.1
• Gene: Usp44 / 314746
• RGDID: 1308216
• Length: 731
• Species: Rattus norvegicus
• Alignment Length: 681
• Identity: 147/681 - (21%)
• Similarity: 234/681 - (34%)
• Gaps: 241/681 - (35%)

  Fly   491 PGPIDNSNLITANPFRNVRTLTGEGGHLKRDTPLVQNHD-------FELV---PKSLW------- 538
            |.|....:|:|.:..:::..|           .|.|.|.       |.:|   .:|:|
  Rat     7 PRPRQTRSLLTMDRCKHIEQL-----------QLAQGHSILNPQKWFCMVCNTTESIWACLSCSH 60

  Fly   539 ---------KALNRWYGDNLPLPRQVIQPPNSDVELELYPLNLRILLHQAQPSQTGVGGGTQLGS 594
                     .||..:...:.|:..:|     :|:.:..|..|..:|       .....|  .|.|
  Rat    61 VACGQYIQEHALKHFEESSHPVAFEV-----NDMYVFCYLCNDYVL-------NDNTAG--DLKS 111

  Fly   595 WGSTVSGGYGVLASGGGYAAIAVS-SVLQPPKRYLAYTAAFSRLATVRQVGEFLCEQLRLKSED- 657
            ..||:|.     ..|..|..:..| |||||..   |...::|...:.:.:.         .|||
  Rat   112 LRSTLSA-----IKGKSYPCVVQSDSVLQPVN---AQADSYSLHDSTQSLP---------GSEDP 159

  Fly   658 --IRLWHVPQLDNGAIL----------------LEEDAMCLKELLIRDND---QLLLEIRNKDLT 701
              ..|||..:...|...                .:|..:..:|:..|..:   |:..|:   :.|
  Rat   160 MCTALWHRRRALMGKTFRTWFEQSPIGRKRQEQTQEKTVAKREVKRRQQELEQQMKAEL---ECT 221

  Fly   702 WPEE------LGSLATAQCGQGAGTP-------------------GDRRRLTRSSIMSVHA--PG 739
            .|.:      |...||.:.......|                   |..:|::.|.|....|  ||
  Rat   222 PPRKSLRLQGLSEAATVEILPVQAPPPPPASPAKEKALALPPSEDGKLKRVSDSLIKRRPAVTPG 286

  Fly   740 ATGLHNLGNTCFMNAALQVLFNTQPLAQYFQREMHRFEVN------------------------- 779
            .|||.||||||:||:.||||.:.....|.|.    :.::|
  Rat   287 VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFL----KLDLNQWLAVAASDKARSYKHSAVTDAATA 347

  Fly   780 AANKLG-----TKGQLAMR-----------------------------YAELLKE-------VWT 803
            ||::|.     .||....|                             |:.|..|       :|:
  Rat   348 AAHQLNEGQEKEKGFACSRHPGLSSGLSGGASKGRNMELIQPREPSSPYSSLCHELHTLFQVMWS 412

  Fly   804 ATTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHEDLNRVMEKPYSELKDSNGRPDK 868
            .....|:|..:...|.|..|.|.|..|.|:||.|..|||.:..:|            ::.|  .|
  Rat   413 GEWALVSPFAMLHSVWKLIPAFRGYAQQDAQEFLCELLDKIQREL------------ETTG--TK 463

  Fly   869 IVAAEAWSQHHARNQ--SIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLPLPVENYIYFEVL 931
            :.|....||.....|  :::.::|:|||.|:|:||.|.::|...:||..|||..| |.|
  Rat   464 LPALIPTSQRRLIEQVLNVVNNIFHGQLLSQVTCLACNNKSNTIEPFWDLSLEFP-ERY------ 521

  Fly   932 VILLDG----SVPIKYGFRLNSDCKYSHLKHKLSTMCSLPPNLMLVCELWNSQIRQVLNDDEKLR 992
              ...|    |.|          |..:.:..|.:...:|...: .||:..||: |:..:....:.
  Rat   522 --QCSGKDAASQP----------CLVTDMLGKFTETEALEGKI-YVCDHCNSK-RRKFSSKPVVL 572

  Fly   993 TQSAKELYVYQLPEQSMRTRSNSGLSMHIEQ 1023
            |::.|:|.:..||:.         |.:|:::
  Rat   573 TEAQKQLMICHLPQV---------LRLHLKR 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	143/658 (22%)
		Peptidase_C19	<1480..1737	CDD:470612
Usp44	XP_038934982.1	zf-UBP	43..104	CDD:460464	11/72 (15%)
		UCH	288..693	CDD:425685	86/355 (24%)