Protein Alignment Usp32 and Usp10

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001421448.1
• Gene: Usp10 / 307905
• RGDID: 1561965
• Length: 795
• Species: Rattus norvegicus
• Alignment Length: 928
• Identity: 168/928 - (18%)
• Similarity: 287/928 - (30%)
• Gaps: 361/928 - (38%)

  Fly   961 STMCSLPPNLMLVCELWNSQIRQVLNDDEKLRTQSAKELYVYQLPEQSMRTRSNS---------- 1015
            ||:....|..:|.|    ...::..:|.||..|.|:    :.|.|..::...|:|
  Rat    81 STLNPQAPEFILGC----PTSKKTPDDIEKDETYSS----IDQYPASALALESSSNAEAETLEND 137

  Fly  1016 ----GLSMHIEQGLKDIQRSSALITSAQDSLSSLSTLQTSSHRASSRVLCNGHVS--GLDVEG-- 1072
                ||..  .:..|..:|.....:..:|.         |...||...|.|||.:  |.:.||
  Rat   138 SGAGGLGQ--RERKKKKKRPPGYYSYLKDG---------SEEGASPAALVNGHATSVGTNSEGVE 191

  Fly  1073 EAEVGTDV------SQCNSNSNYNPIVSTYSGNGSGDNQVHELLPDEAGKVSRCFGKRECMPHSL 1131
            :.|...|:      ..|:|..|...::|        |.......|...|..:|..|..|....:.
  Rat   192 DPEFMVDMLPSVMPRTCDSPQNPMDLIS--------DPVPDSPFPRTLGGDARTAGLPEGCRETD 248

  Fly  1132 F---CFKESLILSSSPENTFMHGAAAQQKRVSSAKLLHT--ESNTSSMSYTNHSGENSMESSLTE 1191
            |   |.....:|.::...........:...|::.|:|.:  |...::.....|:.|:
  Rat   249 FEQPCLPTDNLLRTAVTQPNAGADTTENLAVANGKILESLGEGTAAANGVELHTDES-------- 305

  Fly  1192 PIPLADLEPVSSRNGSGGEDCSYRTSPNDSSGLSTGHTLGASLDVDEQAEEGNAEDHDQPDQITT 1256
                |||:|....:          .||...|.||    :..::.:.:.|:...:..||
  Rat   306 ----ADLDPAKPES----------QSPPAESALS----VSGAISISQPAKSWASLFHD------- 345

  Fly  1257 SQPETSSGV-YSRRSSQPP------------HKAG-----------------KYLVAVHRKIT-- 1289
            |:|.:||.| |......||            .|.|                 :.:..||:.::
  Rat   346 SKPSSSSPVAYVETKCSPPVPSPLASEKQMEVKEGLVPVSEDPVAIKIAELLETVTLVHKPVSLQ 410

  Fly  1290 --------------------------RHDSYFLS-YHKTRPSLFGVPLL--------------IP 1313
                                      .|...|:. |.|.:......|::              :|
  Rat   411 PRGLINKGNWCYINATLQALVACPPMYHLMKFIPLYSKVQRPCTSTPMIDSFVRLMNEFTNMPVP 475

  Fly  1314 NS--------------EGGTHKDLYCAVWLQVSRLLSPLPATTEQANHAADCDDSLGYDFPFTLR 1364
            ..              .|...:..|      :.|||:.:.::..:.....|.::.||    |.|.
  Rat   476 PKPRQALGDKIVRDIRPGAAFEPTY------IYRLLTVIKSSLSEKGRQEDAEEYLG----FILN 530

  Fly  1365 AVKADGLTCAICPWSSFCRGCEIRCNNDYVLQGALPPINAAASNTSTPKMNAKFPSLPNLEAKRT 1429
            .:..:.|:                      |:..|.|.:...|.::.|..:.    :.:.|.:.|
  Rat   531 GLHEEMLS----------------------LKKLLSPTHEKHSVSNGPGSHL----IEDEELEDT 569

  Fly  1430 PEYT------------------ASLSYTPTTKYFEDFTIAIDWDPTALHLRYQSTLE---RLWVD 1473
            .|.:                  |....||.|..|.....::.:..::   :..:||:   .|.:|
  Rat   570 GEGSEDEWEQVGPKNKTSVTRQADFVQTPITGIFGGHIRSVVYQQSS---KESATLQPFFTLQLD 631

  Fly  1474 HETIAI-SRREQVEPVDLNHCLRAFTSEEKLEQWYHCSHCKGKKPATKKLQIWKLPPILIVHLKR 1537
            .::..| :.::.:|.:.....::.:|::.|.|           ...::::.:.||||:|::||||
  Rat   632 IQSDKIRTVQDALESLVARESVQGYTTKTKQE-----------VEVSRRVTLEKLPPVLVLHLKR 685

  Fly  1538 FNCVNGKWVKSQKVV---HFPFDDFDPTPYLASVPQETILRHKELLELKNDAEMTMATNEVVSEL 1599
            |  |..|....||:|   .:|.|
  Rat   686 F--VYEKTGGCQKLVKNIEYPVD------------------------------------------ 706

  Fly  1600 DEIDAPSKEVKEELPNQTGSTKATASPPPTGNILRQSKTKNAVRRQRLISTSLTKTPIVDGEFED 1664
                   .|:..||          .||        ..|.||
  Rat   707 -------LEISREL----------LSP--------GVKNKN------------------------ 722

  Fly  1665 YHQHRLKPDVDQFDPRYRLYAVVSHSG-MLNGGHYIS--YASNATGSWYCYNDSSCREISQKPVI 1726
            :..||          .|||:|||.|.| ...||||.:  :.....| |...:|.:.:.|:|..|:
  Rat   723 FKCHR----------TYRLFAVVYHHGNSATGGHYTTDVFQIGLNG-WLRIDDQTVKVINQYQVV 776

  Fly  1727 DPSA---AYLLFYERKGL 1741
            .|||   ||||:|.|..|
  Rat   777 RPSADRTAYLLYYRRVDL 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	10/40 (25%)
		Peptidase_C19	<1480..1737	CDD:470612	56/265 (21%)
Usp10	NP_001421448.1	G3BP1-binding. /evidence=ECO:0000250|UniProtKB:Q14694	6..21
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	124..165		6/42 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	304..327		10/48 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	547..589		5/45 (11%)