Protein Alignment Usp32 and Usp38

DIOPT Version :10

• Sequence 1: NP_001262074.2
• Gene: Usp32 / 40169
• FlyBaseID: FBgn0036913
• Length: 1779
• Species: Drosophila melanogaster
• Sequence 2: NP_001100888.2
• Gene: Usp38 / 307764
• RGDID: 1311974
• Length: 1041
• Species: Rattus norvegicus
• Alignment Length: 661
• Identity: 136/661 - (20%)
• Similarity: 229/661 - (34%)
• Gaps: 186/661 - (28%)

  Fly   702 WPEELGSLATAQCGQGAGTPGDRRRLTRSSIMSVHAPGATGLHNLGNTCFMNAALQVLFNTQPLA 766
            |..:..:||:.              |:|.|..|  ..|.|||.||||||:||:.||.||    :|
  Rat   422 WTSQSNALASC--------------LSRLSGKS--ETGKTGLINLGNTCYMNSVLQALF----MA 466

  Fly   767 QYFQREMHRFEVNAANKLGTKGQLAMRYAELLKEVWTATTRSVAPLKLRFCVNKYAPQFAGGGQH 831
            ..|:|::....:|..|.|       |:..:.|......|.|.....::.|..:: .|.|....|.
  Rat   467 TEFRRQVLSLNLNGCNSL-------MKKLQHLFAFLAHTQREAYAPRIFFEASR-PPWFTPRSQQ 523

  Fly   832 DSQELLEWLLDALHEDLNRVMEKPYSELKDSNGR----------PDKIVAAEAWSQHHARNQSII 886
            |..|.|.:|||.|||: .::: :..|..|.|.|.          .:|:.............:::|
  Rat   524 DCSEYLRFLLDRLHEE-EKIL-RIQSSHKPSEGLGCTETCLQEVTNKVAVPSESPSTGGSEKTLI 586

  Fly   887 IDLFYGQLKSKVSCLGCGHESVRFDPFSLLSL---PLP-VENYIYFE------------------ 929
            ..:|.|:|::.:.||.|...|.:.:.|:.|||   |.| ||:..:.:
  Rat   587 EKMFGGKLRTHICCLNCRSTSHKVEAFTDLSLAFCPSPSVEDSSFQDPASLPSAQDDGLMQTSVT 651

  Fly   930 ------------VLVILLD--------GSVPIKYGFRLNSDCKYSHLKHKLSTMCSLPPN----- 969
                        ....:.|        ||.|:::....||.......|..:|.  .:|.|
  Rat   652 DAEEEPVVCNPAAAAFVCDSVVNERRLGSPPVEFPCAKNSSVPGESAKILVSK--DVPQNPGGES 714

  Fly   970 LMLVCELWNSQIR-QVLNDDEKLRTQSA-------KELYVYQLPEQSMRT--RSNSGLSMHIEQG 1024
            ...|.:|.|..:. :||..:.:...:|.       |.:.:.:.||..:.|  |.:.....|:.:.
  Rat   715 TTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRK 779

  Fly  1025 LKDIQRSSALITSAQDSLSSLSTLQTSSHRASSRVLCNGHVSGLDVEGEAE--------VGTDVS 1081
            :             .|::|....|:....|.|...|..|..:..|.....|        .||:.:
  Rat   780 I-------------LDNVSLPLVLELPVKRTSLSSLSEGWSADADFTDVNENLAKKLKPSGTEEA 831

  Fly  1082 QC-----------------NSNSNYNPIVSTYSGNGSGDNQVHELLPDEAG-----KVSRCFG-- 1122
            .|                 :|.|.:   ..:|:.|.:|....:::.|....     ..|...|
  Rat   832 FCPKLVPYLLSSVVVHSGVSSESGH---YYSYARNITGTESSYQMRPQSESLSLTPSQSSLLGGE 893

  Fly  1123 ----------KRECMPHSLFCFKESLILSSS-----------PENTFMHGAAAQQKRVSSAKLLH 1166
                      :.:.|....|.|.:|.:..:|           |::|.......:|.|.:..:
  Rat   894 SPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLFYKKQSRTNGVR--- 955

  Fly  1167 TESNTSSMSYTNHSGENSMESSLTEPIPL--------ADLEPVSSRNGSGGEDCSYRTS---PND 1220
             ..|.:|..:.|  ||..::..|.:.|..        .:|...:....:....||:|.:   .||
  Rat   956 -SDNPASGVWVN--GEPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDND 1017

  Fly  1221 SSGLSTGHTLG 1231
            ..| |.|.|.|
  Rat  1018 PPG-SCGPTGG 1027

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	EFh_PI-PLC	198..>251	CDD:333715
		EF-hand motif	198..222	CDD:320029
		EF-hand_7	227..290	CDD:463900
		UBP12	486..>1002	CDD:227847	84/364 (23%)
		Peptidase_C19	<1480..1737	CDD:470612
Usp38	NP_001100888.2	Peptidase_C19H	446..946	CDD:239129	107/531 (20%)