DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Usp32 and usp-33

DIOPT Version :9

Sequence 1:	NP_001262074.2	Gene:	Usp32 / 40169	FlyBaseID:	FBgn0036913	Length:	1779	Species:	Drosophila melanogaster
Sequence 2:	NP_510570.2	Gene:	usp-33 / 181647	WormBaseID:	WBGene00010702	Length:	716	Species:	Caenorhabditis elegans

Alignment Length:	320	Identity:	78/320 - (24%)
Similarity:	125/320 - (39%)	Gaps:	69/320 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   654 KSEDIRLWHVPQLDNGAI--LLEEDAMC-------------------LKELLIRDNDQLL--LEI 695
            |..:.|..||..::...:  ||::...|                   ||....:::|.||  :.:
Worm    62 KQMESRCKHVKDINPSDLSQLLQKKLKCMTCHDSVSFSCAHQDCINSLKSSCCKNSDHLLPHMAV 126

  Fly   696 RNKDLTWPEELGSLATAQCGQGAGTPGDRRRLTRSSIMS-------------VHAPGATGLHNLG 747
            .|.......:..|:...:|  ...|| .:|.||.:...:             :...|..|..|.|
Worm   127 HNHPPILYHDRKSILCTRC--MVYTP-VKRFLTHTKFSTSDKVEQETRKMEPLAFRGLLGYLNFG 188

  Fly   748 NTCFMNAALQVLFNTQPLAQYFQREMHRFEV-------NAANKL-GTKGQLAMRYAELLKEVWTA 804
            |||:|||.||:|.:..|..||.      .|:       |.::.: .|..|:|:....:..:.
Worm   189 NTCYMNAVLQLLGHCSPFTQYL------IELIPPGGWSNCSHDIPKTAIQMALDLRNMYSDF--- 244

  Fly   805 TTRSVAPLKLRFCVNKYAPQFAGGGQHDSQELLEWLLDALHEDLNRVMEKPYSELKDSN-----G 864
            ....::|.|:..||....|.|....|.|:.|.:..|||.|..||     |..||...:|     |
Worm   245 PLPYLSPWKIITCVRNEMPGFECFQQQDASEFMRNLLDILDRDL-----KTCSEYHRTNTLIEMG 304

  Fly   865 RPDKIVAAEAWSQHHARNQSIIIDLFYGQLKSKVSCLGCGHESVRFDPFSLLSLPLPVEN 924
            .|:...|....:.|   .::.|..:|.|.|::::.|..||..|...:.|..||:|:..||
Worm   305 NPEMDYAIAMNAPH---TKTAISAIFQGVLENQIQCHSCGFRSRTIENFLDLSIPIVGEN 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Usp32	NP_001262074.2	FRQ1	186..317	CDD:227455
		UBP12	486..>1002	CDD:227847	78/320 (24%)
		Peptidase_C19	<1480..1737	CDD:351799
usp-33	NP_510570.2	Peptidase_C19	183..546	CDD:239072	57/196 (29%)
usp-33	NP_510570.2	UCH	183..545	CDD:278850	57/196 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910