Protein Alignment Rab8 and RAB3D

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_004274.1
• Gene: RAB3D / 9545
• HGNCID: 9779
• Length: 219
• Species: Homo sapiens
• Alignment Length: 179
• Identity: 90/179 - (50%)
• Similarity: 131/179 - (73%)
• Gaps: 0/179 - (0%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            :.:||:|||||||:|.||||..|||:::|:|...|:||:|||||::|:...:|:|||||||||||
Human    17 QNFDYMFKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQ 81

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            ||:|||||||||||||.:|:|||..::||..:::|...|:..:..:.:.:|:||||:|.|:|.|.
Human    82 ERYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLEDERVVP 146

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANN 181
            .|.|.:||.:.|.:|.|.|||.:|||::.|..|...|..|..:.:|.::
Human   147 AEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEKMNESLEPSS 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	88/165 (53%)
RAB3D	NP_004274.1	Rab3	22..186	CDD:206657	86/163 (53%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		4/8 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		14/15 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..219		1/6 (17%)