Protein Alignment Rab8 and RAB9A

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 68/178 - (38%)
• Similarity: 109/178 - (61%)
• Gaps: 11/178 - (6%)

  Fly     8 LFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRT 72
            |||::|:||.||||:.::.|:..:.|:|....|||::|..:.:|:|...:.:||||||||||||:
Human     7 LFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQERFRS 71

  Fly    73 ITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEK------MLLGNKCELTDKRQV 131
            :.|.:|||:...:|.:.:...:||:|:.||.:  |....|||::      ::||||.:::: |||
Human    72 LRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKK--EFIYYADVKEPESFPFVILGNKIDISE-RQV 133

  Fly   132 SKERGEQLAIEYG-IKFMETSAKASINVEEAFLTLASDIKAKTEKRME 178
            |.|..:....:.| ..:.|||||.:.||..||......:.| ||.|.:
Human   134 STEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLA-TEDRSD 180

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	64/170 (38%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	64/167 (38%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		4/10 (40%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		8/13 (62%)