Protein Alignment Rab8 and RAB11A

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_004654.1
• Gene: RAB11A / 8766
• HGNCID: 9760
• Length: 216
• Species: Homo sapiens
• Alignment Length: 195
• Identity: 89/195 - (45%)
• Similarity: 131/195 - (67%)
• Gaps: 16/195 - (8%)

  Fly     5 YDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQER 69
            ||||||::|||||||||:.:|.||:.:.||....||||::|..|:|::|.|.||.||||||||||
Human     8 YDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQER 72

  Fly    70 FRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKE 134
            :|.||:||||||:|.:|||||.:..::||::.|::.:.::|.:::..||:|||.:|...|.|..:
Human    73 YRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTD 137

  Fly   135 RGEQLAIEYGIKFMETSAKASINVEEAFLTLASDI-KAKTEKRME---------ANN------PP 183
            .....|.:.|:.|:||||..|.|||.||.|:.::| :..::|:|.         :||      ||
Human   138 EARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRRENDMSPSNNVVPIHVPP 202

  Fly   184  183
            Human   203  202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	82/166 (49%)
RAB11A	NP_004654.1	Rab11_like	9..173	CDD:206660	81/163 (50%)