DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and MGC147600

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001072877.1	Gene:	MGC147600 / 780339	XenbaseID:	XB-GENE-1002559	Length:	722	Species:	Xenopus tropicalis

Alignment Length:	175	Identity:	73/175 - (41%)
Similarity:	112/175 - (64%)	Gaps:	12/175 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTI 73
            :|::|.||:.|||:..|.|..::.|.....:|:|:||:::|:.:|.:...||:||||||||||:|
Frog   523 YKIVLAGDAAVGKSSFLMRLCKNEFRGNTSATLGVDFQMKTLVVDGEPTILQLWDTAGQERFRSI 587

  Fly    74 TTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ-------- 130
            ..:|:|.|.|::|:||:|.||||.|::.||..||:..|..:..|::|||.:|   ||
Frog   588 AKSYFRRADGVLLLYDVTCEKSFLNVREWIDMIEDATSEAIPIMMVGNKADL---RQLMAEQGHI 649

  Fly   131 -VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTE 174
             ||...||:|:..||..|.|||||...|:.||.|.||.:::.:.:
Frog   650 CVSTNYGEKLSRTYGALFCETSAKEGSNIVEAVLHLAREVRKRCD 694

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	73/171 (43%)
MGC147600	NP_001072877.1	EF-hand_7	8..65	CDD:372618
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..109
		SMC_prok_B	<124..>332	CDD:274008
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	355..384
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	439..491
		Rab	523..687	CDD:206640	72/166 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910