DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab8 and rab40c

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001035438.1	Gene:	rab40c / 678600	ZFINID:	ZDB-GENE-030515-1	Length:	279	Species:	Danio rerio

Alignment Length:	164	Identity:	76/164 - (46%)
Similarity:	105/164 - (64%)	Gaps:	1/164 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            |:||||.|.||:|||.|||..||....:.:..:.:..:.|||:|..||.||.:::||::|||:||
Zfish     9 KSYDYLLKFLLVGDSDVGKGEILDSLQDGSAESPYAYSSGIDYKTTTILLDGRRVKLELWDTSGQ 73

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            .||.||..:|.|||.||:||||||...||:.|..|||.|:|:|.. |.::|:||:..|..||||.
Zfish    74 GRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIREIDEHAPG-VPRILVGNRLHLAFKRQVP 137

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLA 166
            .|:....|.:.|:.|.|.|...:.||.|:|..|:
Zfish   138 TEQARAYAEKNGMTFFEVSPLCNFNVIESFTELS 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	74/161 (46%)
rab40c	NP_001035438.1	Rab40	9..279	CDD:133321	76/164 (46%)
rab40c	NP_001035438.1	SOCS_Rab40	187..229	CDD:239711
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810