Protein Alignment Rab8 and Rab32

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_080681.1
• Gene: Rab32 / 67844
• MGIID: 1915094
• Length: 223
• Species: Mus musculus
• Alignment Length: 178
• Identity: 60/178 - (33%)
• Similarity: 108/178 - (60%)
• Gaps: 6/178 - (3%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKK-IKLQIWDTAG 66
            :|.::|||:|:||:.|||||.|:.|:....|:..:.:|||:||.::.:..|::. ::||:||.||
Mouse    18 ETREHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAG 82

  Fly    67 QERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENA----SADVEKMLLGNKCELTD 127
            ||||..:|..||:.|:|..:|:||::..:|:.:..|..:::...    .:.:..:||.|||:...
Mouse    83 QERFGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQKK 147

  Fly   128 KRQVSKERGEQLAIEYGIK-FMETSAKASINVEEAFLTLASDIKAKTE 174
            ....|..:.:|...::|.. :.|||||.:||::||...|..::.|..:
Mouse   148 DNSQSPSQMDQFCKDHGFTGWFETSAKDNINIDEATRFLVENMLANQQ 195

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/171 (34%)
Rab32	NP_080681.1	Rab32_Rab38	24..222	CDD:206692	58/172 (34%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q13637	46..60		4/13 (31%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q13637	82..95		7/12 (58%)
		PKA-RII subunit binding domain. /evidence=ECO:0000250	176..195		6/18 (33%)