Protein Alignment Rab8 and Rab2a

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_113906.2
• Gene: Rab2a / 65158
• RGDID: 68323
• Length: 212
• Species: Rattus norvegicus
• Alignment Length: 195
• Identity: 90/195 - (46%)
• Similarity: 133/195 - (68%)
• Gaps: 0/195 - (0%)

  Fly     5 YDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQER 69
            |.||||.::|||:||||:|:|.:|::..|......|||::|..|.|.:|.|:||||||||||||.
  Rat     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQES 67

  Fly    70 FRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKE 134
            ||:||.:|||||.|.:||||||:..:|.::..|:.:..:::::::..||:|||.:|..:|:|.||
  Rat    68 FRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKE 132

  Fly   135 RGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSRTKDS 199
            .||..|.|:|:.|||||||.:.||||||:..|.:|..|.::.:...|....|.::.|..:.|..|
  Rat   133 EGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNAS 197

  Fly   200  199
              Rat   198  197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	83/165 (50%)
Rab2a	NP_113906.2	PLN03108	1..188	CDD:178655	87/184 (47%)
		Required for interaction with PRKCI. /evidence=ECO:0000250	2..19		10/15 (67%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	190..212		2/8 (25%)