DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab8 and rab13

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001025679.1	Gene:	rab13 / 595071	XenbaseID:	XB-GENE-6070728	Length:	201	Species:	Xenopus tropicalis

Alignment Length:	207	Identity:	138/207 - (66%)
Similarity:	171/207 - (82%)	Gaps:	6/207 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |||.||:||||||||||||||||::.|||||:||:|:||||||||||||.|::.||||||:||||
Frog     1 MAKAYDHLFKLLLIGDSGVGKTCLIVRFSEDSFNSTYISTIGIDFKIRTTEIEGKKIKLQVWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            |||||:|||||||||||||:||||||.|:|:|||:||:::|:|||:|.||:|||||||::.:||:
Frog    66 GQERFKTITTAYYRGAMGIILVYDITDERSYENIQNWMKSIKENAAAGVERMLLGNKCDMENKRK 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSR 195
            |.|||||:||.|:||:|.|||||:|.||:|||.|||.||..|..||    :.|.....|....|.
Frog   131 VPKERGEKLAKEHGIRFFETSAKSSQNVDEAFNTLARDILMKISKR----SAPGVKDPLDLKSSS 191

  Fly   196 TKDSWLSRCSLL 207
            .|.|  ::||:|
Frog   192 KKGS--NKCSVL 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	123/165 (75%)
rab13	NP_001025679.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	123/165 (75%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR47980
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110