Protein Alignment Rab8 and RAB13

DIOPT Version :9

• Sequence 1: NP_001246837.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_002861.1
• Gene: RAB13 / 5872
• HGNCID: 9762
• Length: 203
• Species: Homo sapiens
• Alignment Length: 206
• Identity: 132/206 - (64%)
• Similarity: 167/206 - (81%)
• Gaps: 4/206 - (1%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |||.||:||||||||||||||||::.||:||.||.|:||||||||||||::::.||||||:||||
Human     1 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            |||||:|||||||||||||:||||||.|||||||:||:::|:|||||.||::||||||::..||:
Human    66 GQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRK 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSR 195
            |.||:.::||.|:||:|.|||||:|:||:|||.:||.||..|:..|...|........||..|.:
Human   131 VQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCDKK 195

  Fly   196 TKDSWLSRCSL 206
            .    .::|||
Human   196 N----TNKCSL 202

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	119/165 (72%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	119/165 (72%)
		Effector region. /evidence=ECO:0000250	37..45		6/7 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		8/34 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101252
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1998
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.850