Protein Alignment Rab8 and RAB4A

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_004569.2
• Gene: RAB4A / 5867
• HGNCID: 9781
• Length: 218
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 79/174 - (45%)
• Similarity: 113/174 - (64%)
• Gaps: 0/174 - (0%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |::|||:|||.|:||::|.||:|:|.:|.|..|......|||::|..:.|.:..|.:||||||||
Human     6 MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTA 70

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            ||||||::|.:|||||.|.:||||||..:::..:.||:.:....||.::..:|.|||.:|...|:
Human    71 GQERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADRE 135

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTE 174
            |:.....:.|.|..:.|:||||....||||||:..|..|..|.|
Human   136 VTFLEASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIE 179

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	74/165 (45%)
RAB4A	NP_004569.2	Rab4	14..174	CDD:206696	71/159 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	44..49		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	70..79		7/8 (88%)