Protein Alignment Rab8 and RAB3A

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_002857.1
• Gene: RAB3A / 5864
• HGNCID: 9777
• Length: 220
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 97/191 - (50%)
• Similarity: 138/191 - (72%)
• Gaps: 4/191 - (2%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            :.:||:||:|:||:|.||||..|||:::|:|...|:||:|||||::||..::|:|||||||||||
Human    17 QNFDYMFKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQ 81

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            ||:|||||||||||||.:|:||||.|:||..:::|...|:..:..:.:.:|:||||::.|:|.||
Human    82 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMEDERVVS 146

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNP----PKGGHQL 189
            .|||.|||...|.:|.|.|||.:|||::.|..|...|..|..:.::..:|    .|.|.||
Human   147 SERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEKMSESLDTADPAVTGAKQGPQL 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	91/165 (55%)
RAB3A	NP_002857.1	Rab3	22..186	CDD:206657	89/163 (55%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P63012	49..58		4/8 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P63012	80..96		14/15 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..220		5/14 (36%)