DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and rasef

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_699335.4	Gene:	rasef / 570731	ZFINID:	ZDB-GENE-081105-157	Length:	706	Species:	Danio rerio

Alignment Length:	196	Identity:	76/196 - (38%)
Similarity:	117/196 - (59%)	Gaps:	13/196 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTI 73
            ::::|.||:.|||:..|.|..::.|.....:|:|:||:::|:.:|.....||:||||||||||:|
Zfish   508 YRIVLAGDAAVGKSSFLLRLCKNEFKGNTSATLGVDFQMKTLVVDGVPTVLQLWDTAGQERFRSI 572

  Fly    74 TTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ-------- 130
            ..:|:|.|.|::|:||:|.||||.|::.|:..||:.:..|:..||:|||   ||.|:
Zfish   573 AKSYFRRADGVLLLYDVTCEKSFLNVREWVDIIEDVSQDDIPIMLVGNK---TDLRKEALQDGVT 634

  Fly   131 -VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPK-GGHQLKPMD 193
             :....||:||:.|...|.|||||...|:.||.|.||.::....:...|..:..| .|:..|.|.
Zfish   635 CIPTSYGEKLAMTYSALFCETSAKDGSNIIEAVLHLAREVTKHADDYKEPVSVAKLSGNHTKKMS 699

  Fly   194 S 194
            |
Zfish   700 S 700

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	70/171 (41%)
rasef	XP_699335.4	EFh	9..69	CDD:238008
		EF-hand_7	10..68	CDD:290234
		DUF904	201..>253	CDD:283624
		RAB	508..674	CDD:197555	70/168 (42%)
		Rab	508..672	CDD:206640	69/166 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810