Protein Alignment Rab8 and RAB4B

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057238.3
• Gene: RAB4B / 53916
• HGNCID: 9782
• Length: 213
• Species: Homo sapiens
• Alignment Length: 174
• Identity: 79/174 - (45%)
• Similarity: 114/174 - (65%)
• Gaps: 0/174 - (0%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            ||:|||:|||.|:||.:|.||:|:|.:|.|:.|......|||::|..|.:.:..|.:||||||||
Human     1 MAETYDFLFKFLVIGSAGTGKSCLLHQFIENKFKQDSNHTIGVEFGSRVVNVGGKTVKLQIWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            ||||||::|.:|||||.|.:||||||..:::.::..|:.:....||.::..:|.|||.:|..:|:
Human    66 GQERFRSVTRSYYRGAAGALLVYDITSRETYNSLAAWLTDARTLASPNIVVILCGNKKDLDPERE 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTE 174
            |:.....:.|.|..:.|:||||....|||||||..|..|..|.:
Human   131 VTFLEASRFAQENELMFLETSALTGENVEEAFLKCARTILNKID 174

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	74/165 (45%)
RAB4B	NP_057238.3	Rab4	9..169	CDD:206696	71/159 (45%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	39..44		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	65..74		7/8 (88%)