Protein Alignment Rab8 and RAB8B

DIOPT Version :9

• Sequence 1: NP_001246837.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057614.1
• Gene: RAB8B / 51762
• HGNCID: 30273
• Length: 207
• Species: Homo sapiens
• Alignment Length: 207
• Identity: 163/207 - (78%)
• Similarity: 183/207 - (88%)
• Gaps: 0/207 - (0%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |||||||||||||||||||||||:|||||||||||||||||||||||||||||.|||||||||||
Human     1 MAKTYDYLFKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            ||||||||||||||||||||||||||.||||:|||||||||||:||:|||:|:|||||::.||||
Human    66 GQERFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDKRQ 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSR 195
            |||||||:|||:|||||:|||||:|.||||||.|||.||..|..::|..:|....|..:|..::|
Human   131 VSKERGEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNSAGAGGPVKITENR 195

  Fly   196 TKDSWLSRCSLL 207
            :|.:...|||||
Human   196 SKKTSFFRCSLL 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	146/165 (88%)
RAB8B	NP_057614.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	146/165 (88%)
		Effector region. /evidence=ECO:0000250	37..45		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159585
Domainoid	1	1.000	291	1.000	Domainoid score	I1538
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2442
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	1	1.000	-	-		otm40627
orthoMCL	1	0.900	-	-		OOG6_101252
Panther	1	1.100	-	-	O	PTHR47980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1998
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790