Protein Alignment Rab8 and RAB23

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057361.3
• Gene: RAB23 / 51715
• HGNCID: 14263
• Length: 237
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 70/227 - (30%)
• Similarity: 112/227 - (49%)
• Gaps: 31/227 - (13%)

  Fly    10 KLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTIT 74
            |::::|:..|||:.::.|:.:..|...:..|||:||..|.|:::::.::|.:|||||||.|..||
Human    11 KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAIT 75

  Fly    75 TAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQL 139
            .||||||...:||:..|..:|||.:.:|...:.... .|:..:|:.||.:|.|...:..|..|.|
Human    76 KAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEV-GDIPTVLVQNKIDLLDDSCIKNEEAEAL 139

  Fly   140 AIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEAN--------------NPPKGGH--- 187
            |....::|..||.|..:||.|.|..||.....|.::::..:              |...|.|
Human   140 AKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQIAEDPELTHSSSNKIGVFNTSGGSHSGQ 204

  Fly   188 -----------QLKPMDSRTKDSW--LSRCSL 206
                       .|:|...|||.:.  .|.||:
Human   205 NSGTLNGGDVINLRPNKQRTKKNRNPFSSCSI 236

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/161 (36%)
RAB23	NP_057361.3	Rab23_like	10..169	CDD:133306	58/158 (37%)