Protein Alignment Rab8 and RAB6B

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057661.3
• Gene: RAB6B / 51560
• HGNCID: 14902
• Length: 208
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 79/192 - (41%)
• Similarity: 123/192 - (64%)
• Gaps: 14/192 - (7%)

  Fly     9 FKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTI 73
            |||:.:|:..||||.::.||..|:|:.|:.:||||||..:|:.|:::.::||:||||||||||::
Human    14 FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSL 78

  Fly    74 TTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQ 138
            ..:|.|.:...::|||||...||:....||.::.....:||..||:|||.:|.||||::.|.|||
Human    79 IPSYIRDSTVAVVVYDITNLNSFQQTSKWIDDVRTERGSDVIIMLVGNKTDLADKRQITIEEGEQ 143

  Fly   139 LAIEYGIKFMETSAKASINVEEAFLTLAS------DIKAKTEKRM------EANNPP--KGG 186
            .|.|..:.|:|||||...||::.|..:||      :::.|:::.|      :...||  :||
Human   144 RAKELSVMFIETSAKTGYNVKQLFRRVASALPGMENVQEKSKEGMIDIKLDKPQEPPASEGG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	73/168 (43%)
RAB6B	NP_057661.3	Rab6	14..174	CDD:206654	73/159 (46%)
		Switch 1. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	39..49		4/9 (44%)
		Switch 2. /evidence=ECO:0000269|PubMed:16790928, ECO:0007744|PDB:2FE4, ECO:0007744|PDB:2FFQ	71..87		8/15 (53%)