Protein Alignment Rab8 and RAB9B

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_057454.1
• Gene: RAB9B / 51209
• HGNCID: 14090
• Length: 201
• Species: Homo sapiens
• Alignment Length: 194
• Identity: 71/194 - (36%)
• Similarity: 111/194 - (57%)
• Gaps: 18/194 - (9%)

  Fly     8 LFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRT 72
            |.|::|:||.||||:.::.|:..:.|::....|||::|..|.:|:|.:.:.||||||||||||::
Human     7 LLKVILLGDGGVGKSSLMNRYVTNKFDSQAFHTIGVEFLNRDLEVDGRFVTLQIWDTAGQERFKS 71

  Fly    73 ITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEK------MLLGNKCELTDKRQV 131
            :.|.:||||...:|.:.:...:||||:.||.:  |....|||:.      ::||||.:..| |||
Human    72 LRTPFYRGADCCLLTFSVDDRQSFENLGNWQK--EFIYYADVKDPEHFPFVVLGNKVDKED-RQV 133

  Fly   132 SKERGEQLAIEYG-IKFMETSAKASINVEEAFLTLASDIKAKTEK--------RMEANNPPKGG 186
            :.|..:...:|.| ..::|||||...||..||......:.|..|:        .::.|:..|.|
Human   134 TTEEAQTWCMENGDYPYLETSAKDDTNVTVAFEEAVRQVLAVEEQLEHCMLGHTIDLNSGSKAG 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	66/170 (39%)
RAB9B	NP_057454.1	Rab9	3..172	CDD:206697	66/167 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P51151	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P51151	64..78		7/13 (54%)