Protein Alignment Rab8 and Rab43

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001019502.1
• Gene: Rab43 / 500249
• RGDID: 1565300
• Length: 210
• Species: Rattus norvegicus
• Alignment Length: 205
• Identity: 92/205 - (44%)
• Similarity: 133/205 - (64%)
• Gaps: 12/205 - (5%)

  Fly     5 YDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQER 69
            ||:||||:|:||:.|||||::.||...||:....||||:||.::|:|:..|::||||||||||||
  Rat    13 YDFLFKLVLVGDASVGKTCVVQRFKTGAFSARQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQER 77

  Fly    70 FRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKE 134
            |||||.:|||.|.|.:|.|||::..:|.::.:||.::.:.|.:::.::|:|||.:|.|.|:|...
  Rat    78 FRTITQSYYRSANGAILAYDISKRSTFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLADLREVPLA 142

  Fly   135 RGEQLAIEYGIK-FMETSAKASINVEEAFLTLASDIKAKTEKRMEANNP---PKGGHQLKPMDSR 195
            ..:.||..|.|. .:|||||.|.||||||..:|      ||..|....|   .|....:: :||:
  Rat   143 EAQSLAEHYDILCAIETSAKDSSNVEEAFTRVA------TELIMRHGGPMFSEKNTDHIQ-LDSK 200

  Fly   196 -TKDSWLSRC 204
             ..:||...|
  Rat   201 DIAESWGCGC 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	81/166 (49%)
Rab43	NP_001019502.1	Rab19	14..178	CDD:133267	82/169 (49%)
		Effector region. /evidence=ECO:0000250	45..53		4/7 (57%)