DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and rab40b

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_001002524.2	Gene:	rab40b / 436797	ZFINID:	ZDB-GENE-040718-257	Length:	287	Species:	Danio rerio

Alignment Length:	165	Identity:	75/165 - (45%)
Similarity:	104/165 - (63%)	Gaps:	1/165 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAG 66
            ||.||:|.|.||:|||.|||..||....:.:..:.:...:|||:|..||.||.:::|||:|||:|
Zfish    16 AKAYDFLLKFLLVGDSDVGKGEILASLQDGSSESPYGYNMGIDYKTTTILLDGRRVKLQLWDTSG 80

  Fly    67 QERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQV 131
            |.||.||..:|.|||.|::||||||...||:.|..||:.|:|:|.. |.|:|:||:..|..||||
Zfish    81 QGRFCTIFRSYSRGAQGVILVYDITNRWSFDGIDRWIKEIDEHAPG-VPKILVGNRLHLAYKRQV 144

  Fly   132 SKERGEQLAIEYGIKFMETSAKASINVEEAFLTLA 166
            :.|..:......|:.|.|.|...:.|:.|:|..||
Zfish   145 TTEHTQAFVERLGVTFFEVSPLCNFNITESFTELA 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	72/161 (45%)
rab40b	NP_001002524.2	Rab40	17..194	CDD:133321	74/164 (45%)
		RAB	23..185	CDD:197555	70/158 (44%)
		SOCS_Rab40	195..237	CDD:239711
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810