Protein Alignment Rab8 and RAB19

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001008749.2
• Gene: RAB19 / 401409
• HGNCID: 19982
• Length: 217
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 88/193 - (45%)
• Similarity: 131/193 - (67%)
• Gaps: 5/193 - (2%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            :.:|||||::|||||.|||||::..|....:..|..:|||:||.:|::::|.||:|:|:||||||
Human    12 ENFDYLFKIILIGDSNVGKTCVVQHFKSGVYTETQQNTIGVDFTVRSLDIDGKKVKMQVWDTAGQ 76

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            |||||||.:|||.|...::.||:|:..:||:|.:||..||:..:|:|..||:||||:|.:||.|.
Human    77 ERFRTITQSYYRSAHAAIIAYDLTRRSTFESIPHWIHEIEKYGAANVVIMLIGNKCDLWEKRHVL 141

  Fly   133 KERGEQLAIEYG-IKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDS 194
            .|....||.:|| :..:|||||.|.|:||.|:.:|.::.|:....:...:...|    .|:||
Human   142 FEDACTLAEKYGLLAVLETSAKESKNIEEVFVLMAKELIARNSLHLYGESALNG----LPLDS 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	83/166 (50%)
RAB19	NP_001008749.2	Rab19	15..179	CDD:133267	83/163 (51%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	39..54		4/14 (29%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	74..89		12/14 (86%)