DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and Cracr2a

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	XP_006506404.1	Gene:	Cracr2a / 381812	MGIID:	2685919	Length:	751	Species:	Mus musculus

Alignment Length:	171	Identity:	70/171 - (40%)
Similarity:	113/171 - (66%)	Gaps:	0/171 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQE 68
            |.|.|||::.:|||.||||..|.|..|..|:....:|:|||::::|:.:||.::.||:|||||||
Mouse   561 TPDRLFKIVFVGDSAVGKTSFLRRLCEARFSPGMAATVGIDYRVKTVTVDNAQVALQLWDTAGQE 625

  Fly    69 RFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSK 133
            |:|.|:..::|.|.|:.::||:|.::||.:|:.|:.::||.....:..:|||||.:...:|:|.:
Mouse   626 RYRCISQQFFRKADGVAVMYDLTAKQSFLSIRQWLSSVEEAVGDRIPVLLLGNKLDNEKEREVPR 690

  Fly   134 ERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTE 174
            ..|||||.|..:.|.|.||.:..|.:|:.|.||..:|.:.:
Mouse   691 GLGEQLAKENNLIFYECSACSGHNAQESLLHLARLLKEQED 731

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	69/165 (42%)
Cracr2a	XP_006506404.1	PRK12309	<32..132	CDD:183426
		Smc	<142..>428	CDD:224117
		Rab	566..724	CDD:206640	65/157 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900