DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab8 and RAB40AL

DIOPT Version :9

Sequence 1:NP_001246837.1 Gene:Rab8 / 40168 FlyBaseID:FBgn0262518 Length:207 Species:Drosophila melanogaster
Sequence 2:NP_001027004.1 Gene:RAB40AL / 282808 HGNCID:25410 Length:278 Species:Homo sapiens


Alignment Length:203 Identity:78/203 - (38%)
Similarity:112/203 - (55%) Gaps:24/203 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            :.||:|.|.||:||..|||:.||....:....:.:....|||:|..||.||.:::||::|||:||
Human     9 QAYDFLLKFLLVGDRDVGKSEILESLQDGTAESPYSHLGGIDYKTTTILLDGQRVKLKLWDTSGQ 73

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            .||.||..:|.|||.|::|||||....|||.:..||:.|||:|.. |.|:|:||:..|..||||.
Human    74 GRFCTIFRSYSRGAQGVILVYDIANRWSFEGMDRWIKKIEEHAPG-VPKILVGNRLHLAFKRQVP 137

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGGHQLKPMDSRTK 197
            :|:.:..|...|:.|.|.|...:.|:.|:|..||..:..:              |:|        
Human   138 REQAQAYAERLGVTFFEVSPLCNFNIIESFTELARIVLLR--------------HRL-------- 180

  Fly   198 DSWLSRCS 205
             :||.|.|
Human   181 -NWLGRPS 187

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab8NP_001246837.1 Rab8_Rab10_Rab13_like 6..172 CDD:206659 71/165 (43%)
RAB40ALNP_001027004.1 P-loop_NTPase 9..278 CDD:328724 78/203 (38%)
SOCS_Rab40 187..228 CDD:239711 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0078
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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