Protein Alignment Rab8 and RAB21

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_055814.1
• Gene: RAB21 / 23011
• HGNCID: 18263
• Length: 225
• Species: Homo sapiens
• Alignment Length: 182
• Identity: 68/182 - (37%)
• Similarity: 107/182 - (58%)
• Gaps: 2/182 - (1%)

  Fly     7 YLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFR 71
            |.||::|:|:..||||.::.|:.|:.||...|:|:...|..:.:.:..|::.|.||||||||||.
Human    18 YSFKVVLLGEGCVGKTSLVLRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTAGQERFH 82

  Fly    72 TITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERG 136
            .:...|||.:.|.:||||||.|.||:.:|||::.:.:....::...::|||.:|..:|.||.:..
Human    83 ALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGNEICLCIVGNKIDLEKERHVSIQEA 147

  Fly   137 EQLAIEYGIKFMETSAKASINVEEAFLTLASDI--KAKTEKRMEANNPPKGG 186
            |..|...|.|...||||.:..:||.||.|...:  .|:.::|.:.|...:.|
Human   148 ESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQVDERAKGNGSSQPG 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	64/166 (39%)
RAB21	NP_055814.1	Rab21	20..181	CDD:133323	63/160 (39%)