Protein Alignment Rab8 and Rab40c

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_631893.1
• Gene: Rab40c / 224624
• MGIID: 2183454
• Length: 281
• Species: Mus musculus
• Alignment Length: 164
• Identity: 75/164 - (45%)
• Similarity: 104/164 - (63%)
• Gaps: 1/164 - (0%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            |:||||.|.||:|||.|||..||....:.|..:.:..:.|||:|..||.||.:::||::|||:||
Mouse     9 KSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGRRVKLELWDTSGQ 73

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            .||.||..:|.|||.||:||||||...||:.|..||:.|:|:|.. |.::|:||:..|..||||.
Mouse    74 GRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHAPG-VPRILVGNRLHLAFKRQVP 137

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLA 166
            .|:....|.:..:.|.|.|...:.||.|:|..|:
Mouse   138 TEQARAYAEKNCMTFFEVSPLCNFNVIESFTELS 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	73/161 (45%)
Rab40c	NP_631893.1	Rab40	9..281	CDD:133321	75/164 (46%)
		Switch-I. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	41..49		0/7 (0%)
		Switch-II. /evidence=ECO:0000255|PROSITE-ProRule:PRU00753	72..88		9/15 (60%)
		SOCS_Rab40	187..229	CDD:239711
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..281