Protein Alignment Rab8 and Rab5b

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_803130.1
• Gene: Rab5b / 19344
• MGIID: 105938
• Length: 215
• Species: Mus musculus
• Alignment Length: 178
• Identity: 69/178 - (38%)
• Similarity: 108/178 - (60%)
• Gaps: 8/178 - (4%)

  Fly     9 FKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTI 73
            |||:|:|:|.|||:.::.||.:..|:....||||..|..:::.||:..:|.:|||||||||:.::
Mouse    21 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    74 TTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQ 138
            ...|||||...::|||||.:::|...|.|::.::..||..:...|.|||.:|.:||.|..|..:.
Mouse    86 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 150

  Fly   139 LAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKGG 186
            .|.:..:.|||||||.::||.:.||.:|        |::..:.|...|
Mouse   151 YADDNSLLFMETSAKTAMNVNDLFLAIA--------KKLPKSEPQNLG 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	66/162 (41%)
Rab5b	NP_803130.1	Rab5_related	20..182	CDD:206653	67/168 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		5/11 (45%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		8/15 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..215		2/5 (40%)