Protein Alignment Rab8 and Rab22a

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_077756.2
• Gene: Rab22a / 19334
• MGIID: 105072
• Length: 194
• Species: Mus musculus
• Alignment Length: 192
• Identity: 76/192 - (39%)
• Similarity: 115/192 - (59%)
• Gaps: 8/192 - (4%)

  Fly    10 KLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTIT 74
            |:.|:||:||||:.|::||.||:|:.....|||..|..:|::..|:..|..|||||||||||.:.
Mouse     7 KVCLLGDTGVGKSSIVWRFVEDSFDPNINPTIGASFMTKTVQYQNELHKFLIWDTAGQERFRALA 71

  Fly    75 TAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQL 139
            ..||||:...::|||||:|::|..:|||:|.:.::....:...:.||||:|||.|:|.:...:..
Mouse    72 PMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIVVAIAGNKCDLTDVREVMERDAKDY 136

  Fly   140 AIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEANNPPKG--GHQLKPMDSRTKDS 199
            |......|:|||||.:||:.|.|:.::..|.:...      ||..|  |.:|:...|..|.|
Mouse   137 ADSIHAIFVETSAKNAININELFIEISRRIPSTDA------NPASGGKGFKLRRQPSEPKRS 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	68/161 (42%)
Rab22a	NP_077756.2	Rab5_related	5..167	CDD:206653	67/159 (42%)
		Effector region. /evidence=ECO:0000250	34..42		3/7 (43%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..194		8/29 (28%)