DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and Rab10

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_057885.1	Gene:	Rab10 / 19325	MGIID:	105066	Length:	200	Species:	Mus musculus

Alignment Length:	205	Identity:	141/205 - (68%)
Similarity:	162/205 - (79%)	Gaps:	12/205 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            ||||.||||||||||||||||:|||||:|||||||||||||||||:|:||..|||||||||||||
Mouse     4 KTYDLLFKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQ 68

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            |||.||||:|||||||||||||||..||||||..|:|||:|:|:.|||:|||||||::.|||.|.
Mouse    69 ERFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDDKRVVP 133

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKT---EKRMEANNPPKGGHQLKPMDS 194
            |.:|||:|.|:||:|.||||||:||:|:||||||.||..||   |...|..:...||
Mouse   134 KGKGEQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNSENVDISSGG-------- 190

  Fly   195 RTKDSWLSRC 204
             ....|.|:|
Mouse   191 -GVTGWKSKC 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	129/165 (78%)
Rab10	NP_057885.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	129/165 (78%)
Rab10	NP_057885.1	Effector region. /evidence=ECO:0000250	38..46		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1998
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.850