DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab8 and K02E10.1

DIOPT Version :9

Sequence 1:	NP_001246837.1	Gene:	Rab8 / 40168	FlyBaseID:	FBgn0262518	Length:	207	Species:	Drosophila melanogaster
Sequence 2:	NP_508455.2	Gene:	K02E10.1 / 180554	WormBaseID:	WBGene00019317	Length:	218	Species:	Caenorhabditis elegans

Alignment Length:	170	Identity:	81/170 - (47%)
Similarity:	123/170 - (72%)	Gaps:	1/170 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 TYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQE 68
            :|::|||::::||...||:|||.||:|::|....|||:|:|||::||:|...||:|::|||||.|
Worm     2 SYNHLFKIVVVGDHNCGKSCILLRFAENSFRMDHISTLGVDFKLKTIKLGRDKIRLELWDTAGME 66

  Fly    69 RFRTITTAYYRGAMGIMLVYDITQEKSFENI-KNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            |:|||..:||..|.|:|.|||:|.||||||: |.|::.|:::|..:...||:|||.::..:|:|.
Worm    67 RYRTIYNSYYHSAHGVMCVYDMTNEKSFENLEKYWLKEIKQHAPPNAVLMLVGNKADMDQERKVD 131

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAK 172
            .:|.|:||...|:...|.|||..||.||||.||.:.::.:
Worm   132 FDRAEKLASRLGVSLYEVSAKTGINCEEAFHTLTAAMRER 171

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_001246837.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	80/166 (48%)
K02E10.1	NP_508455.2	Rab	7..165	CDD:206640	78/157 (50%)
K02E10.1	NP_508455.2	RAB	7..164	CDD:197555	77/156 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810