Protein Alignment Rab8 and Rab3c

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_598220.2
• Gene: Rab3c / 171058
• RGDID: 620923
• Length: 227
• Species: Rattus norvegicus
• Alignment Length: 196
• Identity: 95/196 - (48%)
• Similarity: 136/196 - (69%)
• Gaps: 15/196 - (7%)

  Fly     3 KTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQ 67
            :.:||:||||:||:|.||||..|||:::|:|.:.|:||:|||||::|:..:.|:|||||||||||
  Rat    25 QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQ 89

  Fly    68 ERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVS 132
            ||:|||||||||||||.:|:||||.|:||..:::|...|:..:..:.:.:|.||||::.|:|.||
  Rat    90 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILAGNKCDMEDERVVS 154

  Fly   133 KERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDI---------------KAKTEKRMEANNP 182
            .|||::|..:.|.:|.|||||.:|||::.|..|...|               .||...|::...|
  Rat   155 TERGQRLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMSESLETDPAITAAKQSTRLKETPP 219

  Fly   183 P 183
            |
  Rat   220 P 220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	90/180 (50%)
Rab3c	NP_598220.2	Rab3	30..194	CDD:206657	88/163 (54%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P10949	53..66		6/12 (50%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P10949	86..104		16/17 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..227		5/19 (26%)