Protein Alignment Rab8 and RAB6D

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001071105.1
• Gene: RAB6D / 150786
• HGNCID: 30272
• Length: 254
• Species: Homo sapiens
• Alignment Length: 205
• Identity: 80/205 - (39%)
• Similarity: 112/205 - (54%)
• Gaps: 19/205 - (9%)

  Fly     9 FKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTI 73
            |||:.:|:..|.||.::.||..|:|:.|:.:.|||||..:|:.|::..|.|::||||||||.|::
Human    14 FKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSL 78

  Fly    74 TTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQ 138
            ...|.|.:...::|||||...||:....||.::.....:||...|:|||.:|.||||||.|.||:
Human    79 IPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTEGGSDVIITLVGNKTDLADKRQVSIEEGER 143

  Fly   139 LAIEYGIKFMETSAKASINVEEAFLTLA-----------------SDIKAKTEKRMEANNPPKGG 186
            .|....:.|:||.|||..||::.|..:|                 |||  |.||..|......|.
Human   144 KAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDI--KLEKPQEQTVSEGGC 206

  Fly   187 HQLKPMDSRT 196
            ....||.|.|
Human   207 SCYSPMSSST 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	71/179 (40%)
RAB6D	NP_001071105.1	Rab6	14..174	CDD:206654	68/159 (43%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		8/17 (47%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)