Protein Alignment Rab8 and Rab1b

DIOPT Version :10

• Sequence 1: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Sequence 2: NP_001103449.1
• Gene: Rab1b / 100126191
• RGDID: 1642882
• Length: 201
• Species: Rattus norvegicus
• Alignment Length: 177
• Identity: 105/177 - (59%)
• Similarity: 140/177 - (79%)
• Gaps: 4/177 - (2%)

  Fly     1 MAKTYDYLFKLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTA 65
            |...|||||||||||||||||:|:|.||::|.:..::|||||:||||||||||.|.|||||||||
  Rat     1 MNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTA 65

  Fly    66 GQERFRTITTAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQ 130
            |||||||||::|||||.||::|||:|.::|:.|:|.|::.|:..||.:|.|:|:|||.:||.|:.
  Rat    66 GQERFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKV 130

  Fly   131 VSKERGEQLAIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRM 177
            |.....::.|...|:.|:|||||.:.|||:||:|:|::||    |||
  Rat   131 VDNTTAKEFADSLGVPFLETSAKNATNVEQAFMTMAAEIK----KRM 173

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	100/165 (61%)
Rab1b	NP_001103449.1	Rab1_Ypt1	7..172	CDD:206661	99/168 (59%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q9H0U4	30..45		6/14 (43%)
		Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4	64..83		16/18 (89%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q9H0U4	65..80		12/14 (86%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..201		1/1 (100%)